Gebinate 120mg Injection
Gebinate 120mg Injection
Introduction to Gebinate 120mg Injection
Gebinate 120mg Injection contains Artesunate, which is a medication primarily utilized for the treatment of malaria, particularly in severe cases. Belonging to the artemisinin class of medications holds a place on the World Health Organization's List of Essential Medicines.
It functions as a prodrug, rapidly converting to its active form, dihydroartemisinin (DHA). This transformation generates reactive oxygen species, inducing oxidative stress and causing damage to malarial proteins. Additionally, it inhibits the essential Plasmodium falciparum exported protein 1 (EXP1), reducing parasite glutathione levels.
While generally well tolerated, common side effects may include a slow heartbeat, allergic reactions, dizziness, and low white blood cell levels. In severe cases, kidney failure requiring dialysis, hemoglobinuria (presence of hemoglobin in urine), and jaundice have been reported.
It is considered safe during pregnancy, particularly in the second and third trimesters, although caution is advised in the first trimester. It is generally safe for use in children, with adjustments in dosing for those under 20 kg. Notably, it should be avoided in newborns when combined with sulfadoxine/pyrimethamine due to potential effects on bilirubin.
In the event of a missed dose, it is crucial to consult with a healthcare professional for guidance on the appropriate course of action. The timing and severity of the missed dose will be considered to determine the most suitable response.
Related Faqs
Where does Aisunate come from?
Derived from the Artemisinin tree this substance is highly sought after for its medicinal properties The Artemisinin tree also known as Sweet Wormwood or Qing Hao in Chinese is a plant native to Asia and has been used for centuries in traditional medicine The active compound extracted from this tree known as Artemisinin has been proven to be effective in treating malaria a deadly disease caused by parasites transmitted through mosquito bites Artemisinin is renowned for its powerful antimalarial properties as it targets and destroys the malaria parasites in the bloodstream This natural compound works by generating free radicals within the parasites causing irreversible damage to their cell membranes and ultimately leading to their death With the rise of drugresistant strains of malaria Artemisinin has become a crucial weapon in the fight against this global health crisis In addition to its antimalarial effects Artemisinin has also shown promise in treating other diseases such as cancer and inflammatory conditions Research has suggested that this natural compound has anticancer properties inhibiting the growth of cancer cells and inducing their death Furthermore it has been found to possess antiinflammatory and immunomodulatory effects making it a potential therapeutic agent for various inflammatory conditions including rheumatoid arthritis and inflammatory bowel disease Overall the remarkable properties of Artemisinin make it a valuable and versatile compound in the field of medicine With ongoing research and development this natural substance holds promise for the treatment of not only malaria but also other diseases afflicting humanity
How does Gebinate work?
The mechanism of action of this substance involves the generation of highly reactive molecules called free radicals which effectively eliminate the malarial parasite known as Plasmodium These free radicals disrupt critical processes within the parasites cells leading to its ultimate demise By targeting the Plasmodium parasite specifically this compound offers a unique and effective approach to combatting malaria one of the most prevalent and deadly infectious diseases in the world The ability to produce free radicals sets this substance apart from traditional antimalarial treatments which often rely on different modes of action such as interfering with the parasites ability to replicate or disrupt its metabolic processes This innovative approach not only offers the potential for high efficacy in treating malaria but also provides an avenue for future development of novel antimalarial therapies By continuing to explore and harness the power of free radicals in the context of antimalarial interventions researchers and scientists hope to further advance the fight against this devastating disease and ultimately improve global health outcomes
Is Gebinate banned in India?
No in India this particular medication is accessible exclusively with a doctors prescription It cannot be obtained or purchased overthecounter without a proper medical authorization The regulations and guidelines surrounding the distribution and use of this medication emphasize the importance of proper medical supervision and evaluation Therefore individuals seeking to acquire this medication must consult with a qualified healthcare professional who can assess their condition provide an accurate diagnosis and prescribe the appropriate treatment Strict adherence to these protocols ensures that individuals receive the proper medical care they require and helps prevent misuse or inappropriate use of the medication It is crucial to prioritize the wellbeing and safety of patients and the necessity for a doctors prescription plays a significant role in achieving this objective Consequently individuals should consult with their healthcare providers to obtain the necessary prescription as selfmedication is strongly discouraged and may have adverse health consequences
Disclaimer : This information is not a substitute for medical advice. Consult your healthcare provider before making any changes to your treatment . Do not ignore or delay professional medical advice based on anything you have seen or read on Medwiki.
Gebinate 120mg Injection
Prescription Required
Packaging :
vial of 1 Injection
Manufacturer :
Oddiant FormulationsComposition :
Artesunate (120mg)MRP :
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