Hashimoto's Thyroiditis: An Unknown Autoimmune Disease.

What are the key stages in the progression of Hashimoto's Thyroiditis, and how does the immune system's response contribute to the inflammation and damage to the thyroid gland?What is Hashimoto's Thyroiditis?Nature of Hashimoto's Thyroiditis:Chronic autoimmune disorder affecting the thyroid gland, responsible for regulating metabolism and growth.Immune System Attack:The immune system mistakenly targets the thyroid, causing inflammation and damage to the gland.Disease Progression Stages:First Stage:Increased production of Th1 cytokines activates macrophages and cytotoxic T cells attacking the thyroid gland.Second Stage:Increased production of Th2 cytokines activates B cells, leading to antibody production against the thyroid.Final Stage:Thyroid gland destruction occurs, resulting in hypothyroidism and reduced thyroid hormone production.Symptoms and Impact:Hashimoto's Thyroiditis manifests with symptoms such as fatigue, weight gain, depression, and joint pain.More prevalent in women, often developing in middle age.Contributing Factors:Development linked to factors like family history of autoimmune disease, exposure to environmental toxins, and iodine deficiency.Diagnosis and Treatment:Diagnosis involves identifying symptoms and specific antibodies in blood tests.Treatment typically includes hormone replacement therapy to address missing thyroid hormones and alleviate symptoms.Disclaimer:- This information is intended to supplement, not substitute, advice from your healthcare provider or doctor. It does not cover all possible uses, precautions, interactions, or side effects, and may not be appropriate for your specific healthcare needs. Always consult with your doctor or another qualified healthcare provider before modifying or discontinuing any prescribed portion of your healthcare plan or treatment, in order to determine the best course of therapy for you. Do not ignore or delay professional medical advice based on anything you have seen or read on Medwiki.Find us at:https://www.instagram.com/medwiki_/?h...https://twitter.com/medwiki_inchttps://www.facebook.com/medwiki.co.in/