Depsol Forte 5 mg25 mg Tablet can be taken with or without food but it is recommended to take it at the same time each day to maintain a consistent level of the medication in your body Follow your doctors instructions regarding the dose and duration of the treatment as this medication can be habitforming If you happen to miss a dose take it as soon as you remember It is important to complete the full course of treatment even if you start feeling better Do not stop taking this medication suddenly without consulting your doctor as it may cause withdrawal effects such as depression and sleep difficulties Some common side effects of this medication include constipation difficulty urinating weight gain confusion and orthostatic hypotension sudden drop in blood pressure upon standing This medication may also cause weight loss If you experience weight loss consider consulting a dietitian for dietary supplements or try increasing your food intake Most of the common side effects are usually mild If they bother you or persist your doctor may suggest ways to prevent or reduce them Serious side effects are rare but if you notice any unusual changes in mood inform your doctor immediately as it may be a sign of suicidal thoughts If you have liver disease be cautious when taking this medication Inform your doctor about all other medications you are taking as some may affect the effectiveness or mode of action of Depsol Forte Also inform your doctor if you are pregnant planning pregnancy or breastfeeding