Introduction to defsol


Defsol is a medication primarily used to treat a condition known as Duchenne muscular dystrophy (DMD) in children aged 5 and older. This condition leads to muscle weakening, and Defsol helps manage its symptoms by reducing inflammation and suppressing the immune system.


Composition of defsol


The active ingredient in Defsol is Deflazacort. It is a type of corticosteroid that works by converting into an active form in the body, which then attaches to the glucocorticoid receptor in cells. This process helps in reducing the production of inflammatory substances.


Uses of defsol


  • Treatment of Duchenne muscular dystrophy (DMD) in children aged 5 and older.
  • Reduces inflammation in the body.
  • Suppresses the immune system to manage symptoms of DMD.

Side effects of defsol


Common side effects:


  • Weight gain
  • Increased appetite
  • Round face (Cushingoid appearance)
  • Upper respiratory infections (common cold)
  • Frequent urination
  • Nose and throat inflammation
  • Excessive hair growth
  • Irritability

Serious side effects:


  • Allergic reactions such as rash, itching, or swelling
  • Severe dizziness
  • Trouble breathing

Precautions of defsol


Defsol should not be taken by individuals who are allergic to it or any of its ingredients. It should be used with caution during pregnancy and breastfeeding. Stopping Defsol suddenly can lead to steroid withdrawal syndrome, which includes symptoms like loss of appetite, nausea, vomiting, tiredness, and headache.


How to Take defsol


  • Take Defsol once daily by mouth.
  • The recommended dose is about 0.9 mg for each kilogram of body weight.
  • It can be taken with or without food.
  • Avoid taking it with grapefruit juice.

Conclusion of defsol


Defsol is an effective medication for managing Duchenne muscular dystrophy in children. By reducing inflammation and suppressing the immune system, it helps alleviate the symptoms associated with this condition. However, it is important to follow the prescribed dosage and take necessary precautions to avoid potential side effects.


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Available in 2 variations

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Defsol 6mg Tablet

strip of 10 tablets

Defsol 30mg Tablet

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Written By:

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Published At: Dec 10, 2024

Updated At: Jan 28, 2025

Reviewed By:

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Published At: Dec 10, 2024

Updated At: Jan 28, 2025

Disclaimer : This information is not a substitute for medical advice. Consult your healthcare provider before making any changes to your treatment . Do not ignore or delay professional medical advice based on anything you have seen or read on Medwiki.