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Introduction to Definal


Definal, also known as Deflazacort, is a medication primarily used to treat a condition called Duchenne muscular dystrophy (DMD). This is a muscle-weakening disease that affects children aged 5 and older. Definal helps manage the symptoms by reducing inflammation and suppressing the immune system.


Composition of Definal


Definal contains the active ingredient Deflazacort. When ingested, it converts into an active form that interacts with the body's cells to reduce inflammation and immune response.


Uses of Definal


  • Treatment of Duchenne muscular dystrophy (DMD) in children aged 5 and older.
  • Reduction of inflammation in the body.
  • Suppression of the immune system to manage symptoms of DMD.

Side Effects of Definal


Common Side Effects:


  • Weight gain
  • Increased appetite
  • Round face (Cushingoid appearance)
  • Upper respiratory infections (common cold)
  • Frequent urination
  • Nose and throat inflammation
  • Excessive hair growth
  • Irritability

Serious Side Effects:


  • Allergic reactions such as rash, itching, or swelling
  • Severe dizziness
  • Trouble breathing

Precautions of Definal


Definal should not be taken by individuals who are allergic to it or any of its ingredients. It should be used with caution during pregnancy and breastfeeding. Stopping Definal suddenly can lead to steroid withdrawal syndrome, which includes symptoms like loss of appetite, nausea, vomiting, tiredness, and headache.


How to Take Definal


  • Take Definal once daily by mouth.
  • The recommended dose is about 0.9 mg for each kilogram of body weight.
  • It can be taken with or without food.
  • Avoid taking it with grapefruit juice.

Conclusion of Definal


Definal is an effective medication for managing Duchenne muscular dystrophy in children. By reducing inflammation and suppressing the immune system, it helps alleviate the symptoms of this muscle-weakening disease. However, it is important to be aware of its side effects and take necessary precautions while using it. Always consult with a healthcare professional before starting or stopping the medication.


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Written By:

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Published At: Dec 10, 2024

Updated At: Jan 28, 2025

Reviewed By:

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Published At: Dec 10, 2024

Updated At: Jan 28, 2025

Disclaimer : This information is not a substitute for medical advice. Consult your healthcare provider before making any changes to your treatment . Do not ignore or delay professional medical advice based on anything you have seen or read on Medwiki.