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Combither AT 120mg Injection contains Artesunate, which is a medication primarily utilized for the treatment of malaria, particularly in severe cases. Belonging to the artemisinin class of medications holds a place on the World Health Organization's List of Essential Medicines.

It functions as a prodrug, rapidly converting to its active form, dihydroartemisinin (DHA). This transformation generates reactive oxygen species, inducing oxidative stress and causing damage to malarial proteins. Additionally, it inhibits the essential Plasmodium falciparum exported protein 1 (EXP1), reducing parasite glutathione levels.

While generally well tolerated, common side effects may include a slow heartbeat, allergic reactions, dizziness, and low white blood cell levels. In severe cases, kidney failure requiring dialysis, hemoglobinuria (presence of hemoglobin in urine), and jaundice have been reported.

It is considered safe during pregnancy, particularly in the second and third trimesters, although caution is advised in the first trimester. It is generally safe for use in children, with adjustments in dosing for those under 20 kg. Notably, it should be avoided in newborns when combined with sulfadoxine/pyrimethamine due to potential effects on bilirubin.

In the event of a missed dose, it is crucial to consult with a healthcare professional for guidance on the appropriate course of action. The timing and severity of the missed dose will be considered to determine the most suitable response.

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Available in 2 variations

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Combither AT 60mg Injection

Combither AT 60mg Injection

Artesunate (60mg)

vial of 1 ml Injection

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Combither AT 120mg Injection

Combither AT 120mg Injection

Artesunate (120mg)

vial of 1 Injection

Related Faqs

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Where does Combither AT come from?

Derived from the Artemisinin tree this natural compound is highly regarded for its medicinal properties With a rich history in traditional Chinese medicine the Artemisinin tree has been used for centuries to treat various ailments The compound extracted from this tree known as Artemisinin has gained significant attention in recent years due to its potent antimalarial properties It has proven to be effective in combating drugresistant strains of malaria making it a valuable tool in the fight against this deadly disease Artemisinins unique mode of action sets it apart from other antimalarial drugs It works by targeting the malaria parasite within the red blood cells effectively killing it and preventing further infection This makes it particularly useful in areas where malaria is prevalent and drug resistance is a growing concern In addition to its antimalarial properties Artemisinin has also shown promise in treating other diseases Research has suggested that it may have potential in fighting certain types of cancer as it has been found to inhibit the growth of cancer cells Furthermore it has displayed antiinflammatory and immunomodulatory effects indicating its potential in treating autoimmune disorders and other inflammatory conditions The discovery and utilization of Artemisinin have revolutionized the treatment of malaria and opened up new possibilities in the field of medicine Its natural origin and proven efficacy make it a valuable asset in the fight against malaria and other diseases Continued research and development in this area hold great promise for the future as scientists strive to unlock the full potential of this remarkable compound

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Is Combither AT 120mg Injection safe?

Combither AT 120mg Injection is considered to be a safe medication when used in the prescribed dose and duration recommended by your doctor It is essential to strictly follow the instructions given by your doctor and not miss any dose It is important to carefully adhere to your doctors advice and communicate any concerns regarding side effects To ensure the utmost safety and effectiveness of Combither AT 120mg Injection it is crucial to use it precisely as directed by your doctor This means not skipping any doses and strictly adhering to the prescribed schedule By doing so you can ensure that the medication works optimally to address your specific condition Furthermore it is vital to follow your doctors instructions concerning the management of any potential side effects Although Combither AT 120mg Injection is generally welltolerated there is a possibility of experiencing side effects If you encounter any discomfort or adverse reactions it is advisable to inform your doctor promptly They can provide you with the necessary guidance and may adjust the dosage or suggest alternative treatment options if required It is important to note that individual responses to medication can vary and what works well for one person may not be suitable for another Therefore it is crucial to have open and honest communication with your doctor throughout your treatment journey Your doctor is there to guide and support you ensuring your wellbeing while using Combither AT 120mg Injection

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How does Falcimax work?

The mechanism of action involves the generation of reactive molecules known as free radicals which effectively eradicate the malarial parasite specifically Plasmodium These free radicals have the ability to disrupt vital cellular processes within the parasite leading to its ultimate demise By generating these highly reactive species the drug displays a targeted approach to combating malaria ensuring that the parasite is specifically targeted while minimizing harm to the host organism This unique mode of action sets it apart from other antimalarial medications making it an effective and valuable tool in the fight against malaria The production of free radicals effectively harnesses the oxidative power of the drug allowing it to selectively destroy Plasmodium and halt the progression of the disease By attacking the parasite at its core this drug offers a promising approach to malaria treatment and prevention and continues to play a pivotal role in global efforts to control this devastating disease

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Is Genuate banned in India?

In India the availability of certain medications is regulated requiring a doctors prescription to obtain them This measure ensures the safety and appropriate usage of these drugs By implementing this system the government aims to protect the public from potential risks associated with selfmedication and inappropriate use of medications While this may seem inconvenient for some it is a necessary step to safeguard the health and wellbeing of individuals in the country Having a doctors prescription serves several purposes Firstly it helps to prevent the misuse or abuse of medications that can have severe consequences on ones health Secondly it allows medical professionals to evaluate the patients condition and history ensuring that the prescribed medication aligns with their specific needs Additionally prescriptions enable doctors to monitor the patients progress and make any necessary adjustments to the treatment plan The process of obtaining a prescription is relatively straightforward Individuals seeking medication must schedule an appointment with a qualified healthcare provider who will assess their medical condition and recommend appropriate treatment Following the consultation the doctor will issue a prescription that can be presented to a licensed pharmacist to obtain the prescribed medication This system ensures that individuals receive the appropriate treatment and minimizes the risks associated with selfdiagnosis and selfmedication

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Is Alpasunate banned in India?

No in India this particular medication can only be obtained with a valid prescription from a licensed doctor It is not available overthecounter and cannot be purchased without proper authorization from a healthcare professional This regulation is in place to ensure the safe and responsible use of the medication as it may carry potential risks and side effects that need to be carefully considered by a qualified medical practitioner Purchasing medications without a prescription can pose serious health hazards and is generally discouraged Thus it is important to consult with a doctor who can assess your specific medical condition review your medical history and provide the necessary guidance on whether this medication is suitable for you Remember your health and wellbeing are of utmost importance and it is always best to follow the advice and recommendations of healthcare professionals to ensure the safe and effective management of your medical needs

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How does Artesar work?

The mechanism of action of this particular compound involves the production of free radicals which have the capacity to effectively target and eliminate the malarial parasite known as Plasmodium By generating these highly reactive molecules this substance is able to disrupt vital processes within the parasite ultimately leading to its demise The production of free radicals is a critical step in the chain of events that result in the destruction of the malarial parasite This compounds unique ability to generate these radicals distinguishes it as an effective weapon against the Plasmodium parasite offering a promising approach for combating malaria As the free radicals are unleashed they directly attack specific targets within the parasite such as key proteins or cell membranes interfering with essential biological processes Consequently the malarial parasite is unable to survive leading to its complete eradication This innovative mechanism of action places this compound at the forefront of antimalarial treatments showcasing its potential for contributing to the global efforts in controlling and ultimately eliminating malaria

Written By:

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Published At: Dec 10, 2024

Updated At: Dec 30, 2024

Reviewed By:

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Published At: Dec 10, 2024

Updated At: Dec 30, 2024

Disclaimer : This information is not a substitute for medical advice. Consult your healthcare provider before making any changes to your treatment . Do not ignore or delay professional medical advice based on anything you have seen or read on Medwiki.