Combither AT 60mg Injection
Combither AT 60mg Injection
Introduction to Combither AT 60mg Injection
Combither AT 60mg Injection contains Artesunate, which is a medication primarily utilized for the treatment of malaria, particularly in severe cases. Belonging to the artemisinin class of medications holds a place on the World Health Organization's List of Essential Medicines.
It functions as a prodrug, rapidly converting to its active form, dihydroartemisinin (DHA). This transformation generates reactive oxygen species, inducing oxidative stress and causing damage to malarial proteins. Additionally, it inhibits the essential Plasmodium falciparum exported protein 1 (EXP1), reducing parasite glutathione levels.
While generally well-tolerated, common side effects may include a slow heartbeat, allergic reactions, dizziness, and low white blood cell levels In severe cases, kidney failure requiring dialysis, hemoglobinuria (presence of hemoglobin in urine), and jaundice have been reported.
It is considered safe during pregnancy, particularly in the second and third trimesters, although caution is advised in the first trimester. It is generally safe for use in children, with adjustments in dosing for those under 20 kg. Notably, it should be avoided in newborns when combined with sulfadoxine/pyrimethamine due to potential effects on bilirubin.
In the event of a missed dose, it is crucial to consult with a healthcare professional for guidance on the appropriate course of action. The timing and severity of the missed dose will be considered to determine the most suitable response.
Related Faqs
Where does Combither AT come from?
Derived from the Artemisinin tree this natural compound is highly regarded for its medicinal properties With a rich history in traditional Chinese medicine the Artemisinin tree has been used for centuries to treat various ailments The compound extracted from this tree known as Artemisinin has gained significant attention in recent years due to its potent antimalarial properties It has proven to be effective in combating drugresistant strains of malaria making it a valuable tool in the fight against this deadly disease Artemisinins unique mode of action sets it apart from other antimalarial drugs It works by targeting the malaria parasite within the red blood cells effectively killing it and preventing further infection This makes it particularly useful in areas where malaria is prevalent and drug resistance is a growing concern In addition to its antimalarial properties Artemisinin has also shown promise in treating other diseases Research has suggested that it may have potential in fighting certain types of cancer as it has been found to inhibit the growth of cancer cells Furthermore it has displayed antiinflammatory and immunomodulatory effects indicating its potential in treating autoimmune disorders and other inflammatory conditions The discovery and utilization of Artemisinin have revolutionized the treatment of malaria and opened up new possibilities in the field of medicine Its natural origin and proven efficacy make it a valuable asset in the fight against malaria and other diseases Continued research and development in this area hold great promise for the future as scientists strive to unlock the full potential of this remarkable compound
How does Combither AT work?
The mechanism of action of this substance involves the generation of free radicals that effectively eliminate the malarial parasite also known as Plasmodium By generating free radicals this substance targets the parasite and disrupts its life cycle ultimately leading to its eradication This process is essential for combating malaria as Plasmodium is responsible for causing the disease in humans Once administered this substance enters the bloodstream and selectively accumulates within the Plasmodiuminfected red blood cells Once inside these cells it undergoes a transformation that generates free radicals These free radicals then initiate a series of chemical reactions within the parasites structure damaging vital components and disrupting essential processes necessary for its survival As a result the malarial parasite is unable to proliferate further and is ultimately eliminated from the body This unique mechanism of action makes this substance a powerful weapon against malaria By selectively targeting the parasite while sparing healthy cells it ensures a highly effective treatment with minimal side effects Additionally its ability to generate free radicals allows for a fast and potent eradication of the parasite contributing to a speedy recovery Overall the utilization of this substance represents a significant advancement in antimalarial treatment and plays a vital role in combating this widespread and deadly disease
Is Falarcin banned in India?
In India the availability of the product you are referring to is limited to individuals who possess a valid prescription from a doctor This means that in order to obtain this particular product one must first consult with a qualified healthcare professional who will evaluate their condition and determine if the product is suitable for their specific needs Following the consultation if the doctor deems it appropriate they will provide a prescription which allows the individual to legally obtain the product from a pharmacy or authorized medical supplier This regulation ensures that the product is used responsibly and under the guidance of a medical professional in order to prioritize the safety and wellbeing of individuals in India It is important to abide by these guidelines and seek professional advice when considering the use of any medication or healthcare product Doing so ensures that individuals receive the appropriate treatment and support for their specific health concerns
Is Arh Plus banned in India?
The availability of this particular medication is restricted to India and can only be obtained with a legitimate prescription from a qualified medical professional It is not accessible overthecounter or through other means without proper authorization This precaution ensures that the medication is used safely and effectively as prescribed by a healthcare provider who has evaluated the individuals specific medical condition and needs Engaging in selfmedication or obtaining the medication without the necessary expertise and supervision can lead to potential risks and adverse effects Therefore it is essential to adhere to the regulations and consult a healthcare practitioner in India to obtain a prescription for this medication By doing so individuals can ensure their health and wellbeing are prioritized while utilizing the medication appropriately for their medical requirements
Is Malart banned in India?
In India the accessibility of certain medications is strictly controlled and monitored One such medicine requiring a doctors prescription is available exclusively through this regulated process This practice aims to ensure the safety and wellbeing of individuals by preventing the misuse or improper administration of potentially harmful drugs By implementing these restrictions the government and medical authorities aim to minimize the risks associated with selfmedication and encourage individuals to consult a healthcare professional for proper diagnosis and prescription This system plays a crucial role in safeguarding public health and upholding ethical standards in the pharmaceutical industry Therefore if one wishes to obtain this particular medicine in India it is essential to consult a qualified doctor who can assess the individuals condition and prescribe the appropriate treatment By following this established protocol individuals can receive the necessary medication while also prioritizing their health and wellbeing
How does Falcimax work?
The mechanism of action involves the generation of reactive molecules known as free radicals which effectively eradicate the malarial parasite specifically Plasmodium These free radicals have the ability to disrupt vital cellular processes within the parasite leading to its ultimate demise By generating these highly reactive species the drug displays a targeted approach to combating malaria ensuring that the parasite is specifically targeted while minimizing harm to the host organism This unique mode of action sets it apart from other antimalarial medications making it an effective and valuable tool in the fight against malaria The production of free radicals effectively harnesses the oxidative power of the drug allowing it to selectively destroy Plasmodium and halt the progression of the disease By attacking the parasite at its core this drug offers a promising approach to malaria treatment and prevention and continues to play a pivotal role in global efforts to control this devastating disease
Disclaimer : This information is not a substitute for medical advice. Consult your healthcare provider before making any changes to your treatment . Do not ignore or delay professional medical advice based on anything you have seen or read on Medwiki.
Combither AT 60mg Injection
Prescription Required
Packaging :
vial of 1 ml Injection
Manufacturer :
Aristo Pharmaceuticals Pvt LtdComposition :
Artesunate (60mg)MRP :
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