--Folic Acid: Allergic reactions, sleep disorders, skin reactions, loss of appetite, nausea, abdominal bloating. Grape Seed Extract: Headache, sore throat, dizziness, itchy scalp, nausea. Lycopene: Low blood pressure, allergic reactions, chest pain, accumulation of fat under the skin, indigestion. Lutein: Skin discoloration, hives or rash, difficulty breathing, tightness in the chest. Zinc: Nausea, vomiting, diarrhea, metallic taste, kidney and stomach damage. Selenium: Nausea, vomiting, nail changes, loss of energy, irritability.