Calsunate 50mg Tablet

Calsunate 50mg Tablet

Prescription Required

Packaging :

strip of 4 tablets

Manufacturer :

Calibar Pharmaceuticals

Composition :

Artesunate (50mg)



Introduction to Calsunate 50mg Tablet

Calsunate 50mg Tablet contains Artesunate, which is a medication primarily utilized for the treatment of malaria, particularly in severe cases Belonging to the artemisinin class of medications,holds a place on the World Health Organization''s List of Essential Medicines

It functions as a prodrug, rapidly converting to its active form, dihydroartemisinin (DHA) This transformation generates reactive oxygen species, inducing oxidative stress and causing damage to malarial proteins Additionally, it inhibits the essential Plasmodium falciparum exported protein 1 (EXP1), reducing parasite glutathione levels


While generally welltolerated, common side effects may include a slow heartbeat, allergic reactions, dizziness, and low white blood cell levels In severe cases, kidney failure requiring dialysis, hemoglobinuria (presence of hemoglobin in urine), and jaundice have been reported


It is considered safe during pregnancy, particularly in the second and third trimesters, although caution is advised in the first trimester It is generally safe for use in children, with adjustments in dosing for those under 20 kg Notably, it should be avoided in newborns when combined with sulfadoxine/pyrimethamine due to potential effects on bilirubin


In the event of a missed dose, it is crucial to consult with a healthcare professional for guidance on the appropriate course of action The timing and severity of the missed dose will be considered to determine the most suitable response


How Calsunate 50mg Tablet Works

Artesunate as a malaria-fighting superhero with a versatile arsenal. Its endoperoxide part acts like a powerful weapon, creating reactive oxygen species (ROS) that disrupt the parasite's defenses. In martial arts fashion, Artesunate inhibits heme polymerization, destabilizes the parasite membrane, and skillfully targets proteins, weakening the enemy. It even takes on a crucial parasite protein called PfATP6, reducing its strength. This superhero's multi-pronged approach makes it a formidable foe for malaria, tackling the parasite with precision and power.

How to take Calsunate 50mg Tablet

This medicine will be provided by your doctor or nurse; please avoid selfadministration
Do not take it on your own; wait for guidance from your doctor or nurse
Trust your healthcare professional to administer the medicine; do not attempt selfadministration

Special Precautions about Calsunate 50mg Tablet

Artesunate is primarily used for the treatment of severe malaria, especially caused by Plasmodium falciparum It is not typically used for uncomplicated malaria It is crucial that the diagnosis of severe malaria is confirmed before initiating treatment with Artesunate
Regular monitoring of liver function is recommended during Artesunate treatment, especially in patients with preexisting liver conditions Elevated liver enzymes may occur, and dose adjustments or discontinuation may be necessary

USES IN Calsunate 50mg Tablet


BENEFITS OF Calsunate 50mg Tablet

Rapid and effective malaria treatment
Improves recovery from malaria
Demonstrates high antimalarial potency

SIDE EFFECTS OF Calsunate 50mg Tablet

Abdominal pain
Decreased white blood cell count
Taste change

What if I Missed a Dose of Calsunate 50mg Tablet

Your doctor or nurse keeps a close eye on when you need it. It''s rare to miss a dose, but if you suspect it, let them know. They''re there to ensure you receive the right treatment at the right time.

Similar Medicines Of Calsunate 50mg Tablet

For information purposes only. Consult a doctor before taking any medicines.

Calsunate 50mg Tablet


Safety Advice For Calsunate 50mg Tablet

Check for risk indication explain below.

High risk Moderate risk Safe

Drug Interaction :

Consult a healthcare provider for accurate interpretation of interactions with Artesunate; seek immediate help if experiencing adverse effects
Note that the absence of interaction does not guarantee no interactions
Exercise caution with drugs like Acetophenazine, Alimemazine, and Artemether, which may increase QTc prolongation
Ambroxol can elevate the risk of methemoglobinemia when combined with Artesunate
Stay vigilant with Articaine, as its combination with Artesunate may also heighten the risk of methemoglobinemia

Drug-Food Interaction

No interactions identified between Artesunate and food; consult a healthcare provider for accurate information and potential drugrelated concerns
Consult your healthcare provider for more information

Habit Forming


Disease Explanation :


Malaria is a disease caused by a parasite that infects some types of mosquitoes. When ... Show More

Disclaimer : This information is not a substitute for medical advice. Consult your healthcare provider before making any changes to your treatment . Do not ignore or delay professional medical advice based on anything you have seen or read on Medwiki.

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