Calsunate 50mg Tablet
Calsunate 50mg Tablet
Introduction to Calsunate 50mg Tablet
Calsunate 50mg Tablet contains Artesunate, which is a medication primarily utilized for the treatment of malaria, particularly in severe cases Belonging to the artemisinin class of medications,holds a place on the World Health Organization''s List of Essential Medicines
It functions as a prodrug, rapidly converting to its active form, dihydroartemisinin (DHA) This transformation generates reactive oxygen species, inducing oxidative stress and causing damage to malarial proteins Additionally, it inhibits the essential Plasmodium falciparum exported protein 1 (EXP1), reducing parasite glutathione levels
While generally welltolerated, common side effects may include a slow heartbeat, allergic reactions, dizziness, and low white blood cell levels In severe cases, kidney failure requiring dialysis, hemoglobinuria (presence of hemoglobin in urine), and jaundice have been reported
It is considered safe during pregnancy, particularly in the second and third trimesters, although caution is advised in the first trimester It is generally safe for use in children, with adjustments in dosing for those under 20 kg Notably, it should be avoided in newborns when combined with sulfadoxine/pyrimethamine due to potential effects on bilirubin
In the event of a missed dose, it is crucial to consult with a healthcare professional for guidance on the appropriate course of action The timing and severity of the missed dose will be considered to determine the most suitable response
Related Faqs
Where does Calsunate come from?
Artemisinin the key ingredient in various antimalarial medications is obtained from the Artemisinin tree This remarkable compound has proven to be highly effective in treating malaria and has played a pivotal role in reducing the global burden of this deadly disease The Artemisinin tree scientifically known as Artemisia annua is native to Asia and has been used in traditional Chinese medicine for centuries The leaves and flowers of this plant contain high concentrations of Artemisinin making it a valuable resource in the fight against malaria The process of obtaining Artemisinin involves extracting the compound from the leaves of the Artemisinin tree Once the leaves are harvested they are subjected to a series of purification and extraction techniques to isolate the precious Artemisinin molecules These molecules are then further processed to produce various formulations of antimalarial medications including tablets injectables and syrup The availability of Artemisininbased medicines has revolutionized malaria treatment and contributed significantly to the decline in malariarelated deaths worldwide Artemisininbased combination therapy ACT which combines Artemisinin with other antimalarial drugs is considered the most effective treatment for uncomplicated malaria This combination therapy not only ensures a rapid reduction in parasite levels but also reduces the risk of developing drug resistance The affordability accessibility and efficacy of Artemisininbased medications have made them a cornerstone of malaria control efforts globally However due to concerns of resistance development it is vital to ensure the sustainable supply of highquality Artemisinin encouraging research into alternative sources and production methods The Artemisinin tree continues to be a valuable asset in the ongoing battle against malaria highlighting natures role in providing lifesaving solutions to global health challenges
Is Calsunate banned in India?
In India the availability of this particular medication is restricted to those who have obtained a valid prescription from a doctor This means that individuals are unable to purchase or acquire the medication without a proper medical recommendation The regulations in place ensure that the medication is used responsibly and under the guidance of a healthcare professional By requiring a doctors prescription authorities aim to safeguard the wellbeing of patients and prevent the misuse or inappropriate use of the medication It is important to adhere to these guidelines and consult with a qualified medical practitioner who can assess an individuals specific needs and recommend the most suitable course of treatment This system not only promotes safety but also encourages individuals to seek professional advice and guidance to ensure optimal health outcomes Therefore to access this medication in India it is crucial to consult with a doctor who can assess your unique condition and prescribe the appropriate treatment plan
How does Calsunate work?
The mechanism of action involves the generation of free radicals which play a crucial role in eliminating the malarial parasite known as Plasmodium This unique process targets the parasites vital structures and disrupts their functionality ultimately leading to its demise By producing free radicals this mechanism effectively weakens the parasites defense mechanisms and prevents it from further proliferating within the human body This approach proves particularly effective against the complex life cycle of Plasmodium as it directly attacks the parasite at multiple stages including the liver and blood stages The generation of free radicals offers a highly targeted and powerful strategy to combat malaria as it ensures the parasites destruction while minimizing harm to the human host Furthermore this method has proven successful against a wide range of Plasmodium species making it an essential weapon in the fight against this devastating disease Through its ability to produce free radicals this mechanism not only presents an effective treatment option for malaria but also contributes to ongoing efforts to eradicate the disease globally
How does Falno work?
The mechanism of action involves the generation of free radicals which effectively eradicates the malarial parasite known as Plasmodium This process plays a crucial role in combating the harmful effects of malaria By producing these highly reactive molecules the medication targets the parasite and disrupts its vital functions leading to its eventual demise These free radicals possess a remarkable ability to destroy the intricate structure of the Plasmodium parasite effectively neutralizing its growth and reproduction This innovative mode of action ensures the elimination of the parasite thereby alleviating the symptoms of malaria and preventing its further progression The selective action of this medication on the malarial parasite guarantees a targeted approach maximizing the efficacy of treatment and minimizing potential side effects Ultimately through the generation of free radicals this drug demonstrates its effectiveness in eradicating the Plasmodium parasite offering hope to those afflicted with malaria and contributing to the global efforts in combating this widespread and devastating disease
How does Maxinate work?
The mechanism of action of this substance involves the generation of free radicals which effectively exterminate the Plasmodium parasite responsible for causing malaria By producing these highly reactive particles this substance exhibits a potent antimalarial effect The free radicals generated upon administration of this substance target the vital structures and metabolic processes of the malarial parasite leading to its eradication By disrupting the parasites normal functioning this substance effectively halts the progression of the disease and promotes the elimination of the infection This unique mechanism of action sets this substance apart as an efficient and effective option in the fight against malaria Its ability to specifically target and eliminate the Plasmodium parasite showcases its potential to combat this widespread and lifethreatening disease By harnessing the power of free radicals this substance offers a promising strategy for inhibiting the growth and survival of the malarial parasite ultimately contributing to the global efforts to control and eliminate malaria
Disclaimer : This information is not a substitute for medical advice. Consult your healthcare provider before making any changes to your treatment . Do not ignore or delay professional medical advice based on anything you have seen or read on Medwiki.
Calsunate 50mg Tablet
Prescription Required
Packaging :
strip of 4 tablets
Manufacturer :
Calibar PharmaceuticalsComposition :
Artesunate (50mg)MRP :
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