cabisunate

Cabisunate 120mg Injection contains Artesunate, which is a medication primarily utilized for the treatment of malaria, particularly in severe cases. Belonging to the artemisinin class of medications holds a place on the World Health Organization's List of Essential Medicines.

It functions as a prodrug, rapidly converting to its active form, dihydroartemisinin (DHA). This transformation generates reactive oxygen species, inducing oxidative stress and causing damage to malarial proteins. Additionally, it inhibits the essential Plasmodium falciparum exported protein 1 (EXP1), reducing parasite glutathione levels.

While generally well tolerated, common side effects may include a slow heartbeat, allergic reactions, dizziness, and low white blood cell levels. In severe cases, kidney failure requiring dialysis, hemoglobinuria (presence of hemoglobin in urine), and jaundice have been reported.

It is considered safe during pregnancy, particularly in the second and third trimesters, although caution is advised in the first trimester. It is generally safe for use in children, with adjustments in dosing for those under 20 kg. Notably, it should be avoided in newborns when combined with sulfadoxine/pyrimethamine due to potential effects on bilirubin.

In the event of a missed dose, it is crucial to consult with a healthcare professional for guidance on the appropriate course of action. The timing and severity of the missed dose will be considered to determine the most suitable response.

Available in 2 variations

Cabisunate 60mg Injection

Artesunate (60mg)

vial of 1 Injection

MRP : ₹213

Cabisunate 120mg Injection

Artesunate (120mg)

vial of 1 Injection

MRP : ₹406

Related Faqs

How does Falcimax work?

The mechanism of action involves the generation of reactive molecules known as free radicals which effectively eradicate the malarial parasite specifically Plasmodium These free radicals have the ability to disrupt vital cellular processes within the parasite leading to its ultimate demise By generating these highly reactive species the drug displays a targeted approach to combating malaria ensuring that the parasite is specifically targeted while minimizing harm to the host organism This unique mode of action sets it apart from other antimalarial medications making it an effective and valuable tool in the fight against malaria The production of free radicals effectively harnesses the oxidative power of the drug allowing it to selectively destroy Plasmodium and halt the progression of the disease By attacking the parasite at its core this drug offers a promising approach to malaria treatment and prevention and continues to play a pivotal role in global efforts to control this devastating disease

Where does Arinatem come from?

Artemisinin a compound with potent antimalarial properties is sourced from the Artemisinin tree This tree also known as sweet wormwood or Qing Hao in traditional Chinese medicine has been used for centuries in the treatment of various ailments The extraction of artemisinin from the leaves of this tree revolutionized the field of malaria treatment offering a more effective and fasteracting solution compared to conventional drugs Artemisinins remarkable effectiveness against malaria is attributed to its unique chemical structure which allows it to target and eliminate the malaria parasites in the blood When ingested artemisinin reacts with iron from the parasites producing free radicals that damage the parasites cellular structures leading to their demise This mode of action sets artemisinin apart from other antimalarial drugs and has contributed to its widespread use in combating malaria particularly in regions where drug resistance has become a significant concern In addition to its antimalarial properties artemisinin has shown promising potential in treating various other diseases and conditions Recent studies have indicated its effectiveness against certain types of cancer including leukemia and breast cancer It has also demonstrated antiinflammatory immunosuppressive and antiviral activities Although further research is needed to harness its full therapeutic potential artemisinins versatility and unique mode of action make it a promising candidate for future drug development Overall the derivation of artemisinin from the Artemisinin tree has led to significant advancements in the treatment of malaria and holds promise for tackling other diseases Its natural origin and potent properties make it a valuable resource in the ongoing battle against global health challenges

How does Artesar work?

The mechanism of action of this particular compound involves the production of free radicals which have the capacity to effectively target and eliminate the malarial parasite known as Plasmodium By generating these highly reactive molecules this substance is able to disrupt vital processes within the parasite ultimately leading to its demise The production of free radicals is a critical step in the chain of events that result in the destruction of the malarial parasite This compounds unique ability to generate these radicals distinguishes it as an effective weapon against the Plasmodium parasite offering a promising approach for combating malaria As the free radicals are unleashed they directly attack specific targets within the parasite such as key proteins or cell membranes interfering with essential biological processes Consequently the malarial parasite is unable to survive leading to its complete eradication This innovative mechanism of action places this compound at the forefront of antimalarial treatments showcasing its potential for contributing to the global efforts in controlling and ultimately eliminating malaria

Where does Aisunate come from?

Derived from the Artemisinin tree this substance is highly sought after for its medicinal properties The Artemisinin tree also known as Sweet Wormwood or Qing Hao in Chinese is a plant native to Asia and has been used for centuries in traditional medicine The active compound extracted from this tree known as Artemisinin has been proven to be effective in treating malaria a deadly disease caused by parasites transmitted through mosquito bites Artemisinin is renowned for its powerful antimalarial properties as it targets and destroys the malaria parasites in the bloodstream This natural compound works by generating free radicals within the parasites causing irreversible damage to their cell membranes and ultimately leading to their death With the rise of drugresistant strains of malaria Artemisinin has become a crucial weapon in the fight against this global health crisis In addition to its antimalarial effects Artemisinin has also shown promise in treating other diseases such as cancer and inflammatory conditions Research has suggested that this natural compound has anticancer properties inhibiting the growth of cancer cells and inducing their death Furthermore it has been found to possess antiinflammatory and immunomodulatory effects making it a potential therapeutic agent for various inflammatory conditions including rheumatoid arthritis and inflammatory bowel disease Overall the remarkable properties of Artemisinin make it a valuable and versatile compound in the field of medicine With ongoing research and development this natural substance holds promise for the treatment of not only malaria but also other diseases afflicting humanity

How does Cabisunate work?

The mechanism of action of this compound involves the generation of free radicals which effectively eliminate the malarial parasite known as Plasmodium These free radicals are highly reactive molecules that possess the ability to cause damage to the essential cellular components of the parasite including its genetic material and proteins By disrupting the normal functioning of these vital components the compound effectively hampers the parasites ability to survive and replicate within the human body Through the generation of free radicals this compound carries out a targeted attack on the Plasmodium parasite These free radicals have the capability to interact with and damage specific molecules critical for the parasites survival including enzymes and membranes Such interactions disrupt the normal biochemical processes and structural integrity of the parasite ultimately leading to its demise This unique mechanism of action sets this compound apart from conventional antimalarial drugs as it specifically targets the parasite while minimizing potential harm to the human host Additionally the formation of free radicals occurs selectively within the malarial parasite further minimizing any potential offtarget effects in the human body Overall the generation of free radicals by this compound provides an effective means of eradicating the malarial parasite By specifically targeting and damaging essential components of the parasite this compound represents a promising approach in the fight against malaria

Where does Cabisunate come from?

Derived from the Artemisinin tree this incredible compound has revolutionized the world of medicine With its unparalleled potency and remarkable therapeutic properties it has become a cornerstone in the battle against malaria Artemisinin a natural product extracted from the Artemisinin tree offers hope to millions of people afflicted by this deadly disease The Artemisinin tree native to certain regions of Asia has long been recognized for its medicinal properties However it wasnt until the discovery of artemisinin that its true potential was unleashed This powerful compound possesses strong antimalarial activity making it a vital tool in the fight against this global health crisis Artemisinin works by targeting the parasite responsible for malaria disrupting their life cycle and ultimately leading to their demise Its unique mechanism of action different from other available antimalarial drugs has proven highly effective in treating both uncomplicated and severe forms of the disease Moreover this compound has demonstrated a remarkable safety profile making it suitable for use in various populations including pregnant women and children Its rapid action along with its ability to rapidly clear the malaria parasite from the bloodstream has contributed to its growing popularity in malariaendemic areas In addition to its antimalarial properties artemisinin has shown promise in the treatment of other diseases such as certain types of cancer Ongoing research is exploring its potential applications in combating various forms of cancer providing new hope for patients worldwide The discovery and development of artemisinin have undoubtedly transformed the field of medicine Its natural origin potent antimalarial activity and potential therapeutic applications make it a valuable asset in the quest for better health outcomes for millions

Written By:

DRx. Anchal Kumar VermaMaster of Pharmacy

Published At: Dec 10, 2024

Updated At: Jan 28, 2025

Reviewed By:

DRx Ashwani SinghMaster in Pharmacy

Published At: Dec 10, 2024

Updated At: Jan 28, 2025

Disclaimer : This information is not a substitute for medical advice. Consult your healthcare provider before making any changes to your treatment . Do not ignore or delay professional medical advice based on anything you have seen or read on Medwiki.

Find us at:

cabisunate

Prescription Required

Manufacturer :

Cablin Healthcare Pvt Ltd

Composition :

artesunate

MRP :

₹213 - ₹406