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Bionate 60mg Injection

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Bionate 60mg Injection

Introduction to Bionate 60mg Injection

Bionate 60mg Injection contains Artesunate, which is a medication primarily utilized for the treatment of malaria, particularly in severe cases. Belonging to the artemisinin class of medications holds a place on the World Health Organization's List of Essential Medicines.

It functions as a prodrug, rapidly converting to its active form, dihydroartemisinin (DHA). This transformation generates reactive oxygen species, inducing oxidative stress and causing damage to malarial proteins. Additionally, it inhibits the essential Plasmodium falciparum exported protein 1 (EXP1), reducing parasite glutathione levels.

While generally well-tolerated, common side effects may include a slow heartbeat, allergic reactions, dizziness, and low white blood cell levels In severe cases, kidney failure requiring dialysis, hemoglobinuria (presence of hemoglobin in urine), and jaundice have been reported.

It is considered safe during pregnancy, particularly in the second and third trimesters, although caution is advised in the first trimester. It is generally safe for use in children, with adjustments in dosing for those under 20 kg. Notably, it should be avoided in newborns when combined with sulfadoxine/pyrimethamine due to potential effects on bilirubin.

In the event of a missed dose, it is crucial to consult with a healthcare professional for guidance on the appropriate course of action. The timing and severity of the missed dose will be considered to determine the most suitable response.

Related Faqs

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Is Falarcin banned in India?

In India the availability of the product you are referring to is limited to individuals who possess a valid prescription from a doctor This means that in order to obtain this particular product one must first consult with a qualified healthcare professional who will evaluate their condition and determine if the product is suitable for their specific needs Following the consultation if the doctor deems it appropriate they will provide a prescription which allows the individual to legally obtain the product from a pharmacy or authorized medical supplier This regulation ensures that the product is used responsibly and under the guidance of a medical professional in order to prioritize the safety and wellbeing of individuals in India It is important to abide by these guidelines and seek professional advice when considering the use of any medication or healthcare product Doing so ensures that individuals receive the appropriate treatment and support for their specific health concerns

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Is Arh Plus banned in India?

The availability of this particular medication is restricted to India and can only be obtained with a legitimate prescription from a qualified medical professional It is not accessible overthecounter or through other means without proper authorization This precaution ensures that the medication is used safely and effectively as prescribed by a healthcare provider who has evaluated the individuals specific medical condition and needs Engaging in selfmedication or obtaining the medication without the necessary expertise and supervision can lead to potential risks and adverse effects Therefore it is essential to adhere to the regulations and consult a healthcare practitioner in India to obtain a prescription for this medication By doing so individuals can ensure their health and wellbeing are prioritized while utilizing the medication appropriately for their medical requirements

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Is Malart banned in India?

In India the accessibility of certain medications is strictly controlled and monitored One such medicine requiring a doctors prescription is available exclusively through this regulated process This practice aims to ensure the safety and wellbeing of individuals by preventing the misuse or improper administration of potentially harmful drugs By implementing these restrictions the government and medical authorities aim to minimize the risks associated with selfmedication and encourage individuals to consult a healthcare professional for proper diagnosis and prescription This system plays a crucial role in safeguarding public health and upholding ethical standards in the pharmaceutical industry Therefore if one wishes to obtain this particular medicine in India it is essential to consult a qualified doctor who can assess the individuals condition and prescribe the appropriate treatment By following this established protocol individuals can receive the necessary medication while also prioritizing their health and wellbeing

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How does Bionate work?

The mechanism of action involves the generation of free radicals that effectively eradicate the malarial parasite known as Plasmodium These free radicals target the parasites essential components disrupting their functioning and ultimately leading to the parasites demise By producing and releasing these highly reactive chemical species the medication exerts its potent antimalarial effects Plasmodium the causative agent of malaria relies on specific enzymes and molecular processes to survive within the human body However when this medication is administered it undergoes a transformation generating reactive free radicals as a metabolic byproduct These free radicals then interact with critical biomolecules within the parasite including proteins lipids and nucleic acids The interaction between the produced free radicals and the parasites biomolecules disrupts their structural integrity and impairs their normal function Consequently the essential cellular processes of the parasite become compromised rendering it unable to replicate and propagate The parasites ability to evade the immune system is undermined and its survival is severely compromised By specifically targeting the Plasmodium parasite this medication acts as a highly effective antimalarial agent Its unique mechanism of action ensures that it specifically attacks the malarial parasite while minimizing harm to the host This targeted approach makes it an essential tool in the global effort to combat malaria and reduce its devastating impact on human health

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Where does Bionate come from?

Artemisinin a vital compound is extracted from the Artemisinin tree This tree scientifically known as Artemisia annua has been extensively used in traditional Chinese medicine for centuries With its origins traced back to China this tree is also commonly referred to as sweet wormwood or qing hao The unique and potent properties of Artemisinin extracted from the tree have made it an essential component in the treatment of malaria one of the deadliest diseases worldwide Artemisininbased combination therapy ACT is the recommended firstline treatment for malaria particularly in areas where the malaria parasite has developed resistance to other antimalarial drugs This compound works by attacking the Plasmodium parasite responsible for causing malaria effectively reducing the number of parasites in the bloodstream Due to its efficacy and fastacting nature Artemisinin has played a significant role in the global efforts to combat malaria and has saved countless lives In addition to malaria treatment Artemisinin shows potential in treating other diseases such as cancer Research has indicated that this compound exhibits anticancer properties by targeting and killing cancer cells selectively This has led to further studies and clinical trials to explore the full potential of Artemisinin in cancer treatment potentially providing new avenues for patients affected by this deadly disease Overall Artemisinin derived from the Artemisinin tree is a remarkable compound with significant therapeutic potential Whether in the context of malaria treatment or as a potential anticancer agent this natural extract continues to demonstrate its vital importance in the field of medicine

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How does Falcimax work?

The mechanism of action involves the generation of reactive molecules known as free radicals which effectively eradicate the malarial parasite specifically Plasmodium These free radicals have the ability to disrupt vital cellular processes within the parasite leading to its ultimate demise By generating these highly reactive species the drug displays a targeted approach to combating malaria ensuring that the parasite is specifically targeted while minimizing harm to the host organism This unique mode of action sets it apart from other antimalarial medications making it an effective and valuable tool in the fight against malaria The production of free radicals effectively harnesses the oxidative power of the drug allowing it to selectively destroy Plasmodium and halt the progression of the disease By attacking the parasite at its core this drug offers a promising approach to malaria treatment and prevention and continues to play a pivotal role in global efforts to control this devastating disease

Written By:

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Published At: Oct 19, 2023

Updated At: Sep 19, 2024

Reviewed By:

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Published At: Oct 19, 2023

Updated At: Sep 19, 2024

Disclaimer : This information is not a substitute for medical advice. Consult your healthcare provider before making any changes to your treatment . Do not ignore or delay professional medical advice based on anything you have seen or read on Medwiki.