Aisunate 120mg Injection
Aisunate 120mg Injection
Introduction to Aisunate 120mg Injection
Aisunate 120mg Injection contains Artesunate, which is a medication primarily utilized for the treatment of malaria, particularly in severe cases. Belonging to the artemisinin class of medications holds a place on the World Health Organization's List of Essential Medicines.
It functions as a prodrug, rapidly converting to its active form, dihydroartemisinin (DHA). This transformation generates reactive oxygen species, inducing oxidative stress and causing damage to malarial proteins. Additionally, it inhibits the essential Plasmodium falciparum exported protein 1 (EXP1), reducing parasite glutathione levels.
While generally well tolerated, common side effects may include a slow heartbeat, allergic reactions, dizziness, and low white blood cell levels. In severe cases, kidney failure requiring dialysis, hemoglobinuria (presence of hemoglobin in urine), and jaundice have been reported.
It is considered safe during pregnancy, particularly in the second and third trimesters, although caution is advised in the first trimester. It is generally safe for use in children, with adjustments in dosing for those under 20 kg. Notably, it should be avoided in newborns when combined with sulfadoxine/pyrimethamine due to potential effects on bilirubin.
In the event of a missed dose, it is crucial to consult with a healthcare professional for guidance on the appropriate course of action. The timing and severity of the missed dose will be considered to determine the most suitable response.
Related Faqs
How does Aisunate work?
The mechanism of action involves the generation of reactive oxygen species commonly known as free radicals which play a crucial role in eliminating the malarial parasite Plasmodium These free radicals possess a highly reactive nature and are capable of causing significant damage to various components of the parasites cells This leads to the disruption of vital biological processes ultimately resulting in the parasites death Upon administration the medication initiates a series of chemical reactions within the parasites cellular environment It interacts with specific targets such as proteins or enzymes triggering a cascade of events that culminate in the production of free radicals These free radicals are highly unstable and seek to stabilize themselves by reacting with nearby molecules causing oxidative damage to essential cellular components This oxidative stress disturbs the parasites metabolic pathways impairs its ability to replicate and survive and ultimately leads to its demise By specifically targeting the Plasmodium parasite the medication minimizes the impact on the hosts cells reducing the risk of adverse effects It is important to note that this mechanism of action is not exclusive to malarial parasites Free radicals can potentially affect other microorganisms as well highlighting the broadspectrum activity of this medication against various pathogens However its efficacy against Plasmodium and its role in combating malaria make it a valuable tool in the battle against this global health threat
Where does Aisunate come from?
Derived from the Artemisinin tree this substance is highly sought after for its medicinal properties The Artemisinin tree also known as Sweet Wormwood or Qing Hao in Chinese is a plant native to Asia and has been used for centuries in traditional medicine The active compound extracted from this tree known as Artemisinin has been proven to be effective in treating malaria a deadly disease caused by parasites transmitted through mosquito bites Artemisinin is renowned for its powerful antimalarial properties as it targets and destroys the malaria parasites in the bloodstream This natural compound works by generating free radicals within the parasites causing irreversible damage to their cell membranes and ultimately leading to their death With the rise of drugresistant strains of malaria Artemisinin has become a crucial weapon in the fight against this global health crisis In addition to its antimalarial effects Artemisinin has also shown promise in treating other diseases such as cancer and inflammatory conditions Research has suggested that this natural compound has anticancer properties inhibiting the growth of cancer cells and inducing their death Furthermore it has been found to possess antiinflammatory and immunomodulatory effects making it a potential therapeutic agent for various inflammatory conditions including rheumatoid arthritis and inflammatory bowel disease Overall the remarkable properties of Artemisinin make it a valuable and versatile compound in the field of medicine With ongoing research and development this natural substance holds promise for the treatment of not only malaria but also other diseases afflicting humanity
Disclaimer : This information is not a substitute for medical advice. Consult your healthcare provider before making any changes to your treatment . Do not ignore or delay professional medical advice based on anything you have seen or read on Medwiki.
Aisunate 120mg Injection
Prescription Required
Packaging :
vial of 1 Injection
Manufacturer :
Ai Health Care LLPComposition :
Artesunate (120mg)MRP :
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