Actamase 1000 mg/125 mg Injection is a combination medicine consisting of an antibiotic, Cefepime, and Tazobactam.

Cefepime acts by disrupting the formation of bacteria's outer protective layer, the cell wall, crucial for their survival. It achieves this by blocking protein production. Tazobactam enhances the antibiotic's efficacy by inhibiting an enzyme called beta lactamase, which bacteria use to destroy antibiotics In simpler terms, Cefepime breaks down the bacteria's armor, while Tazobactam prevents the bacteria from defending themselves against the antibiotic.

Cefepime and Tazobactam will be provided by your doctor or nurse; self administration should be avoided Trust your healthcare professional to administer the medicine; do not attempt self administration.

Common side effects of Cefepime and Tazobactam may include nausea, stomach pain, indigestion, and diarrhea.

Cefepime may cause neurotoxicity, especially in patients with renal impairment. Dosage adjustments may be necessary in such cases, and monitoring for neurological symptoms, such as seizures or encephalopathy, is recommended Antibiotic use, including Cefepime, may lead to the overgrowth of Clostridioides difficile bacteria, causing severe diarrhea and colitis. If diarrhea occurs during or after treatment, it should be evaluated for possible C difficile infection. Dosage adjustments are often required in patients with impaired renal function, as both Cefepime and Tazobactam are primarily excreted by the kidneys Regular monitoring of renal function is advisable during prolonged therapy.

If a dose of Cefepime and Tazobactam is missed, take it when you remember. If the next dose is close, skip the missed one and stay on the regular schedule. Avoid taking two doses at once Consult your doctor for guidance on managing missed doses effectively.