Can I use Zoxicam if I have a deranged renal function?

Can I use Zoxicam for a migraine?

Zoxicam is not approved for the treatment of migraine. Research studies have shown that Zoxicam is effective in significantly decreasing the pain associated with migraine without aura.

Can Zoxicam be used with methocarbamol?

Yes. Methocarbamol can be used with Zoxicam as no serious side effects are known. Inform your doctor before starting any of the medication.

What is the difference between Zoxicam and meloxicam?

Both Zoxicam and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Zoxicam.

Can Zoxicam be used with diuretics?

No. Zoxicam should not be used with diuretics. Zoxicam reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.

What is the difference between Zoxicam and naproxen?

Both Zoxicam and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Zoxicam.

Can Zoxicam lead to skin reactions?

Yes. Zoxicam is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.

Can Zoxicam be used with warfarin?

No. Zoxicam should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.

Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Zoxicam?

Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.

Is Zoxicam effective in back pain management?

Yes. It can be given for decreasing the back pain. However, you should consult your doctor for the exact cause of your back pain and then start the treatment. Do not self-medicate yourself with Zoxicam as the cause of back pain can be different for different person.

Can I use Zoxicam if I have peptic ulcer disease?

No. Zoxicam is contraindicated in cases of active peptic ulcer disease. Zoxicam is known to cause gastric ulceration and bleeding.

Can Zoxicam be used with lithium?

No. Zoxicam should not be used with lithium. Zoxicam leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.

What are the serious side effects of Zoxicam?

GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.

Can I use Zoxicam if I am a diabetic?

Zoxicam in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Zoxicam so taking piroxicam can lead to increased risk of renal failure by many folds.

Can Zoxicam be used to treat menstrual cramp?

Zoxicam is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.

Can Zoxicam be used in the treatment of allergy?

No. Zoxicam is not a drug to treat allergy. It is a pain killer.

Can Zoxicam be used with Tizanidine?

Yes, Zoxicam can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.

Can Zoxicam be used along with dexamethasone?

No. Zoxicam should not be used with dexamethasone. They both increase each others toxicity. There is an increased risk of GI ulceration.

Is Zoxicam a narcotic?

No. Zoxicam is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.

Can Zoxicam be used in the treatment of chikungunya?

Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Zoxicam or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Zoxicam.

Is Zoxicam a NSAID?

Yes. Zoxicam is a non-steroidal anti-inflammatory drug (NSAID).

What are the contraindications for Zoxicam?

Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.

Can you get high by using Zoxicam?

No. Zoxicam is not known to cause high. It is a non-narcotic painkiller.

What is the difference between Zoxicam and tramadol?

Zoxicam is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.

Why is beta cyclodextrin added to Zoxicam?

Yes. Zoxicam can be combined with beta-cyclodextrin. Research has shown that combining Zoxicam with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.

How long does Zoxicam work?

Zoxicam is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.

Is Zoxicam a muscle relaxant?

No. Zoxicam is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.

Can Zoxicam be used along with paracetamol?

Yes. Paracetamol can be used with Zoxicam as no serious side effects are known. Inform your doctor before starting any of the medication.

Can Zoxicam be used with calcium channel blocker?

Yes. Zoxicam can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)

Are Zoxicam and aspirin same?

No. Zoxicam and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.

What is the difference between Zoxicam and ketoprofen?

Both Zoxicam and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Zoxicam. Ketoprofen gel also showed excellent tolerability.

Is Zoxicam a blood thinner?

No. Zoxicam is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.

Can you donate blood when on the medication with Zoxicam?

Yes. You can donate blood when on Zoxicam. Do inform your doctor before donating blood.

Can Zoxicam be used with Lisinopril?

No. Zoxicam should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Zoxicam.