Liver and Spleen Damage from Dengue: Pathogenesis

What are some common preventive measures that individuals can take to reduce the risk of dengue virus infection?

• Dengue virus, transmitted by mosquitoes, enters the human body through infected mosquito bites.

• The virus primarily infects white blood cells, specifically monocytes and macrophages, crucial for the immune response.

• Infected cells spread the virus to various body parts, including the liver and spleen.

• The liver filters blood and eliminates toxins, while the spleen filters blood and removes old or damaged red blood cells.

• Dengue virus causes inflammation and damage to liver and spleen cells, triggering an immune response.

• Immune cells release cytokines and chemokines, attracting more immune cells and causing further organ damage.

• Symptoms of liver and spleen damage include abdominal pain, nausea, vomiting, and jaundice.

• Severe cases may lead to liver failure and bleeding disorders.

• Preventive measures, such as using mosquito repellent and wearing protective clothing, are crucial to avoid dengue virus infection.

Disclaimer:- This information is intended to supplement, not substitute, advice from your healthcare provider or doctor. It does not cover all possible uses, precautions, interactions, or side effects, and may not be appropriate for your specific healthcare needs. Always consult with your doctor or another qualified healthcare provider before modifying or discontinuing any prescribed portion of your healthcare plan or treatment, in order to determine the best course of therapy for you. Do not ignore or delay professional medical advice based on anything you have seen or read on Medwiki. 

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