Vadadustat
Anemia
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
NA
Controlled Drug Substance
No
vadadustat
Summary
Vadadustat is used to treat anemia, which is a condition where you have fewer red blood cells than normal, in patients with chronic kidney disease. This condition can cause fatigue and weakness.
Vadadustat works by stimulating the production of red blood cells. It belongs to a class of drugs called hypoxia-inducible factor prolyl hydroxylase inhibitors, which help the body respond to low oxygen levels.
Vadadustat is typically taken once daily, with or without food, as prescribed by your doctor. It's important to follow your doctor's specific dosing instructions for the best results.
Common side effects of Vadadustat include nausea and headache. Most people tolerate the medication well, but if you experience any new or worsening symptoms, consult your doctor.
Avoid alcohol while taking Vadadustat, as it can interfere with the medication's effectiveness. Do not take Vadadustat if you're allergic to it or its ingredients. Always consult your doctor about any health conditions before starting this medication.
Indications and Purpose
How does Vadadustat work?
Vadadustat works by stimulating the production of red blood cells. It belongs to a class of drugs called hypoxia-inducible factor prolyl hydroxylase inhibitors. Think of it like turning on a switch that tells your body to make more red blood cells. This helps improve hemoglobin levels, which is the protein in red blood cells that carries oxygen.
Is Vadadustat effective?
Vadadustat is effective for treating anemia in patients with chronic kidney disease. It works by stimulating the production of red blood cells. Clinical studies show Vadadustat improves hemoglobin levels, which is the protein in red blood cells that carries oxygen. This helps manage anemia symptoms and improves quality of life.
What is Vadadustat?
Vadadustat is a medication used to treat anemia in patients with chronic kidney disease. It works by stimulating the production of red blood cells, which helps improve hemoglobin levels. This medication is part of a class of drugs called hypoxia-inducible factor prolyl hydroxylase inhibitors, which help the body respond to low oxygen levels.
Directions for Use
For how long do I take Vadadustat?
Vadadustat is usually a long-term medication for managing anemia in chronic kidney disease. You'll typically take Vadadustat every day as a lifelong treatment unless your doctor suggests otherwise. How long you'll need this medication depends on your body's response, any side effects you experience, and changes in your overall health. Always talk with your doctor before changing or stopping your Vadadustat treatment.
How do I dispose of Vadadustat?
If you can, bring unused Vadadustat to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of this medicine properly so it doesn't harm people or the environment. If you can't find a take-back program, you can throw most medicines in the trash at home. But first, take them out of their original containers, mix them with something undesirable like used coffee grounds, seal the mixture in a plastic bag, and throw it away.
How do I take Vadadustat?
Vadadustat is usually taken as prescribed by your doctor. It's important to follow the specific instructions given to you. Typically, you take it once daily, with or without food. If you miss a dose, take it when you remember unless it's almost time for your next dose. Then just skip the missed dose and continue your normal schedule. Never take two doses at once. Always follow your doctor's specific advice about diet and fluid intake while taking this medication.
How long does it take for Vadadustat to start working?
Vadadustat begins working in your body shortly after you take it. However, you may not notice all the benefits right away. It may take several weeks to see significant improvements in your hemoglobin levels. How quickly the medication works can depend on your overall health and kidney function. Take it exactly as prescribed for the best results.
How should I store Vadadustat?
Store Vadadustat at room temperature, away from moisture and light. Keep it in a tightly closed container. Don't store it in humid places like bathrooms. Always store Vadadustat out of children's reach to prevent accidental swallowing. Check the expiration date regularly and properly dispose of any unused or expired medication.
What is the usual dose of Vadadustat?
The usual starting dose of Vadadustat for adults is determined by your doctor based on your specific health needs. It's typically taken once daily. Your doctor may adjust your dose as needed. Always follow your doctor's specific dosing instructions. Special populations, such as children or the elderly, may require different dosing.
Warnings and Precautions
Can I take Vadadustat with other prescription drugs?
Vadadustat may interact with other medications, increasing the risk of side effects or reducing effectiveness. It's important to tell your doctor about all medicines you take, including over-the-counter drugs and supplements. Your doctor will help manage any potential interactions to ensure your treatment is safe and effective.
Can Vadadustat be taken safely while breastfeeding?
The safety of Vadadustat while breastfeeding isn't well-established. It's important to discuss with your doctor if you're breastfeeding or planning to breastfeed. Your doctor can help determine the best treatment options for you and your baby, considering the potential risks and benefits of using Vadadustat during breastfeeding.
Can Vadadustat be taken safely while pregnant?
The safety of Vadadustat during pregnancy isn't well-established. It's important to discuss with your doctor if you're pregnant or planning to become pregnant. Your doctor can help create a treatment plan that protects both you and your baby, considering the potential risks and benefits of using Vadadustat during pregnancy.
Does Vadadustat have adverse effects?
Adverse effects are unwanted reactions to a medication. Vadadustat can cause some adverse effects, but most people tolerate it well. Common effects include nausea and headache. Serious effects are rare but require immediate medical attention. Always tell your doctor about any new or worsening symptoms while taking Vadadustat.
Does Vadadustat have any safety warnings?
Yes, Vadadustat has important safety warnings. It can increase the risk of serious side effects, so it's crucial to follow your doctor's instructions. Not adhering to safety warnings can lead to severe health issues. Always discuss any concerns or symptoms with your healthcare provider to ensure safe use of the medication.
Is it safe to drink alcohol while taking Vadadustat?
It's best to avoid alcohol while taking Vadadustat. Alcohol can interfere with the medication's effectiveness and may increase the risk of side effects. If you do choose to drink occasionally, limit how much alcohol you consume and talk with your doctor about alcohol use while taking Vadadustat to get personalized advice.
Is it safe to exercise while taking Vadadustat?
You can exercise while taking Vadadustat, but keep a few things in mind. This medication can cause dizziness or fatigue, which might affect your exercise capacity. To exercise safely, drink plenty of water before, during, and after physical activity. Watch for signs of dizziness or unusual fatigue and talk with your doctor if you have concerns.
Is it safe to stop Vadadustat?
Stopping Vadadustat suddenly can cause serious problems for your health conditions. Always talk with your doctor before stopping Vadadustat. They might suggest gradually reducing your dose or switching to a different medication to keep your condition under control. Your doctor will help you make any medication changes safely to protect your health.
Is Vadadustat addictive?
Vadadustat is not addictive or habit-forming. This medication doesn't cause dependency or withdrawal symptoms when you stop taking it. You won't experience cravings for this medication or feel compelled to take more than prescribed. If you have concerns about medication dependence, you can feel confident that Vadadustat doesn't carry this risk.
Is Vadadustat safe for the elderly?
Elderly patients may be more vulnerable to the side effects of Vadadustat. It's important for older adults to be closely monitored by their healthcare provider while taking this medication. Your doctor will consider your overall health and any other medications you're taking to ensure Vadadustat is safe and effective for you.
What are the most common side effects of Vadadustat?
Side effects are unwanted reactions that can happen when taking a medication. With Vadadustat, these effects vary from person to person. Common side effects include nausea and headache. If you notice new symptoms after starting Vadadustat, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking Vadadustat?
Don't take Vadadustat if you're allergic to it or its ingredients. Serious allergic reactions require immediate medical help. Vadadustat shouldn't be used by people with certain health conditions, so always consult your doctor about any concerns. Your doctor will determine if Vadadustat is safe for you based on your health history.
