Tenapanor
Irritable Bowel Syndrome
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Drug Status
Government Approvals
US(FDA)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
Sodium-Hydrogen Exchanger 3 Inhibitor
Controlled Drug Substance
No
Tenapanor
Summary
Tenapanor is used to treat irritable bowel syndrome with constipation, which is a condition causing stomach pain and infrequent bowel movements.
Tenapanor works by reducing sodium absorption in the intestines, which increases water in the intestines and helps soften stools, making bowel movements easier.
The usual dose for adults is 50 mg taken twice daily, just before breakfast and dinner. It is taken orally, which means by mouth.
The most common side effect of Tenapanor is diarrhea, which means frequent, loose, or watery bowel movements. Other effects include abdominal pain and nausea.
Do not take Tenapanor if you have a bowel obstruction, which is a blockage in the intestines. It is not recommended for children under 6 years old due to severe diarrhea risk.
Indications and Purpose
How does Tenapanor work?
Tenapanor works by blocking a protein in the intestines that absorbs sodium. This action increases water in the intestines, softening stools and promoting bowel movements. Think of it like adding water to a dry sponge, making it easier to move through the intestines.
Is Tenapanor effective?
Tenapanor is effective for treating irritable bowel syndrome with constipation (IBS-C). It works by reducing the absorption of sodium in the intestines, which helps increase bowel movements. Clinical studies show that Tenapanor significantly improves symptoms in people with IBS-C.
What is Tenapanor?
Tenapanor is a medication used to treat irritable bowel syndrome with constipation (IBS-C). It works by reducing the absorption of sodium in the intestines, which helps increase bowel movements. This medication is taken orally and is usually part of a long-term treatment plan.
Directions for Use
For how long do I take Tenapanor?
Tenapanor is usually a long-term medication for managing irritable bowel syndrome with constipation (IBS-C). You'll typically take it every day as a lifelong treatment unless your doctor suggests otherwise. Always talk with your doctor before changing or stopping your Tenapanor treatment.
How do I dispose of Tenapanor?
Bring unused Tenapanor to a drug take-back program or collection site at a pharmacy or hospital. If you can't find a take-back program, mix the medication with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away.
How do I take Tenapanor?
Take Tenapanor as prescribed by your doctor, usually twice daily, just before breakfast and dinner. Swallow the tablet whole; do not crush or chew it. Take it on an empty stomach, at least 1 hour before or 2 hours after a meal. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. Do not double up on doses.
How long does it take for Tenapanor to start working?
Tenapanor begins working shortly after you take it, but it may take a few days to notice improvements in bowel movements. The full therapeutic effect can take a few weeks. Individual factors like your overall health can affect how quickly you see results.
How should I store Tenapanor?
Store Tenapanor at room temperature, away from moisture and light. Keep it in a tightly closed container. Do not store it in the bathroom. Keep it out of reach of children and pets. Check the expiration date regularly and dispose of any expired medication properly.
What is the usual dose of Tenapanor?
The usual starting dose of Tenapanor for adults is 50 mg taken twice daily, just before breakfast and dinner. Your doctor may adjust your dose based on your response to the medication. Always follow your doctor's specific dosing instructions for your personal health needs.
Warnings and Precautions
Can I take Tenapanor with other prescription drugs?
There are no major drug interactions known for Tenapanor. However, always inform your doctor about all the medications you are taking to avoid potential interactions. This helps ensure your treatment is safe and effective.
Can Tenapanor be taken safely while breastfeeding?
The safety of Tenapanor while breastfeeding is not well-established. It's unknown if the medication passes into breast milk. If you're breastfeeding, talk with your doctor about safer medication options that would allow you to nurse your baby safely.
Can Tenapanor be taken safely while pregnant?
The safety of Tenapanor during pregnancy is not well-established. Animal studies show potential risks, but human data is limited. If you're pregnant or planning to become pregnant, talk with your doctor about the safest way to manage your condition.
Does Tenapanor have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of Tenapanor include diarrhea, which affects more than 10% of users. Serious side effects are rare but can include severe dehydration. If you experience severe or persistent side effects, contact your doctor immediately.
Does Tenapanor have any safety warnings?
Yes, Tenapanor has safety warnings. It can cause diarrhea, which may lead to dehydration. Drink plenty of fluids to stay hydrated. If you experience severe diarrhea, stop taking Tenapanor and contact your doctor. Not adhering to these warnings can lead to serious health issues.
Is it safe to drink alcohol while taking Tenapanor?
It's best to avoid alcohol while taking Tenapanor. Alcohol can worsen side effects like dehydration and diarrhea. If you choose to drink, limit your intake and watch for symptoms like dizziness or stomach pain. Talk with your doctor about alcohol use while taking Tenapanor.
Is it safe to exercise while taking Tenapanor?
You can exercise while taking Tenapanor, but be cautious. This medication can cause diarrhea and dehydration, which might make you feel dizzy during exercise. Drink plenty of water before, during, and after physical activity. If you feel dizzy or weak, stop exercising and rest.
Is it safe to stop Tenapanor?
Stopping Tenapanor suddenly may cause your symptoms to return. Always talk with your doctor before stopping the medication. They might suggest gradually reducing your dose or switching to a different medication to keep your condition under control.
Is Tenapanor addictive?
Tenapanor is not addictive or habit-forming. This medication doesn't cause dependency or withdrawal symptoms when you stop taking it. You won't experience cravings for this medication or feel compelled to take more than prescribed. If you have concerns about medication dependence, you can feel confident that Tenapanor doesn't carry this risk.
Is Tenapanor safe for the elderly?
Elderly individuals may be more sensitive to the side effects of Tenapanor, such as diarrhea and dehydration. It's important to monitor for these effects and stay well-hydrated. Always consult your doctor about the safety of Tenapanor for your specific health needs.
What are the most common side effects of Tenapanor?
Side effects are unwanted reactions that can happen when taking a medication. The most common side effect of Tenapanor is diarrhea, affecting more than 10% of people. If you notice new symptoms after starting Tenapanor, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking Tenapanor?
Do not take Tenapanor if you have a bowel obstruction, which is a blockage in the intestines. This medication is not recommended for children under 6 years old due to the risk of severe diarrhea. Always consult your doctor about any concerns.
