Tavaborole

Onychomycosis

Drug Status

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Government Approvals

US(FDA)

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WHO Essential Medicine

NO

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Known Teratogen

No

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Pharmaceutical Class

Oxaborole Antifungal

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Controlled Drug Substance

No

Summary

  • Tavaborole is used to treat toenail fungus, which is a fungal infection that affects the nail, causing discoloration and thickening. It helps eliminate the infection by stopping the fungus from growing.

  • Tavaborole works by inhibiting an enzyme called leucyl-tRNA synthetase, which is essential for fungal protein synthesis. This action stops the fungus from growing and spreading, effectively cutting off its "food supply."

  • Tavaborole is applied topically, which means directly on the skin, to the affected toenail once daily. Ensure the nail is clean and dry before application, and use the provided brush to apply the solution evenly.

  • Common side effects of tavaborole include redness, itching, or irritation at the application site. These effects are usually mild and temporary. Serious adverse effects are rare but can include severe allergic reactions.

  • Tavaborole is for external use only and should not be ingested. Avoid contact with eyes, mouth, or other mucous membranes. If severe irritation or an allergic reaction occurs, stop using it and seek medical help.

Indications and Purpose

How does tavaborole work?

Tavaborole works by inhibiting an enzyme called leucyl-tRNA synthetase, which is essential for fungal protein synthesis. This action stops the fungus from growing and spreading. Think of it like cutting off the fungus's "food supply," leading to its elimination. This helps clear the toenail infection over time.

Is tavaborole effective?

Yes, tavaborole is effective in treating toenail fungus. It works by inhibiting an enzyme essential for fungal growth, leading to the elimination of the infection. Clinical studies have shown significant improvement in nail appearance and reduction of fungal presence with regular use as directed.

What is tavaborole?

Tavaborole is an antifungal medication used to treat toenail fungus. It works by inhibiting an enzyme essential for fungal growth, leading to the elimination of the infection. Tavaborole is applied topically to the affected toenail and is used alone, not in combination with other therapies.

Directions for Use

For how long do I take tavaborole?

Tavaborole is used for long-term treatment of toenail fungus. It may take several months to see full results, as toenails grow slowly. Continue using it as prescribed by your doctor, even if you see improvement, to ensure the infection is fully treated. Consult your doctor for guidance.

How do I dispose of tavaborole?

Dispose of unused tavaborole by taking it to a drug take-back program or collection site at a pharmacy. If unavailable, mix it with undesirable substances like coffee grounds, seal in a plastic bag, and throw it in the trash. This prevents harm to people and the environment.

How do I take tavaborole?

Tavaborole is applied once daily to the affected toenail. Make sure the nail is clean and dry before application. Use the provided brush to apply the solution evenly over the entire toenail surface and under the tip. Let it dry completely. If you miss a dose, apply it as soon as you remember. Do not double up on doses. Follow your doctor's instructions for the best results.

How long does it take for tavaborole to start working?

Tavaborole starts working soon after application, but visible improvement in toenail appearance may take several months. Full therapeutic effects depend on nail growth, which is slow. Factors like nail thickness and severity of infection can affect how quickly you see results. Use it as prescribed for best outcomes.

How should I store tavaborole?

Store tavaborole at room temperature, away from moisture and light. Keep it in its original container, tightly closed. Do not refrigerate or freeze it. Avoid storing it in humid places like bathrooms. Keep it out of reach of children to prevent accidental ingestion. Check expiration dates regularly.

What is the usual dose of tavaborole?

The usual dose of tavaborole for adults is to apply it once daily to the affected toenail. There are no specific dose adjustments for children or the elderly, but always follow your doctor's instructions. If you have any concerns about the dosage or application, consult your healthcare provider for personalized advice.

Warnings and Precautions

Can I take tavaborole with other prescription drugs?

Tavaborole is applied topically and has minimal systemic absorption, so it has a low risk of interacting with other prescription drugs. However, always inform your doctor about all medications you are taking to ensure safe and effective treatment. They can provide personalized advice based on your health needs.

Can tavaborole be taken safely while breastfeeding?

The safety of tavaborole while breastfeeding is not well-established. It's unclear if it passes into breast milk. Consult your doctor before using tavaborole if you are breastfeeding. They can help assess the risks and benefits and suggest the safest treatment options for you and your baby.

Can tavaborole be taken safely while pregnant?

The safety of tavaborole during pregnancy is not well-established. Limited data is available, so it's best to consult your doctor if you're pregnant or planning to become pregnant. They can help weigh the benefits and risks and suggest the safest treatment options for your condition.

Does tavaborole have adverse effects?

Adverse effects are unwanted reactions to a medication. With tavaborole, common adverse effects include skin irritation at the application site. These effects are usually mild. Serious adverse effects are rare but can include severe allergic reactions. If you notice any new or worsening symptoms, contact your doctor for advice.

Does tavaborole have any safety warnings?

Yes, tavaborole has safety warnings. It's for external use only and should not be ingested. Avoid contact with eyes, mouth, or other mucous membranes. If you experience severe irritation or an allergic reaction, stop using it and seek medical help. Not adhering to these warnings can lead to adverse effects or ineffective treatment.

Is it safe to drink alcohol while taking tavaborole?

Yes, you can drink alcohol while using tavaborole. There are no known interactions between tavaborole and alcohol. However, it's always a good idea to drink alcohol in moderation and discuss any concerns with your doctor, especially if you have other health conditions or are taking other medications.

Is it safe to exercise while taking tavaborole?

Yes, it's safe to exercise while using tavaborole. This medication is applied topically and does not affect your exercise capacity. However, ensure your toenails are clean and dry before applying the medication, especially if you sweat during exercise. Consult your doctor if you have any concerns.

Is it safe to stop tavaborole?

Yes, you can stop using tavaborole safely, but it's important to complete the full course as prescribed to effectively treat the fungal infection. Stopping early may result in incomplete treatment and recurrence of the infection. Always consult your doctor before making changes to your treatment plan.

Is tavaborole addictive?

No, tavaborole is not addictive. It does not have habit-forming potential and does not cause dependency or withdrawal symptoms. Tavaborole works by affecting the nail fungus directly and does not influence brain chemistry. You can use it as prescribed without worrying about addiction.

Is tavaborole safe for the elderly?

Yes, tavaborole is generally safe for the elderly. However, older adults may have more sensitive skin, so monitor for any irritation at the application site. If any adverse effects occur, consult your doctor. They can provide guidance on safe and effective use for elderly patients.

What are the most common side effects of tavaborole?

Side effects are unwanted reactions to a medication. Common side effects of tavaborole include redness, itching, or irritation at the application site. These effects are usually mild and temporary. If you experience persistent or severe side effects, consult your doctor. They can help determine if the symptoms are related to tavaborole or another cause.

Who should avoid taking tavaborole?

Tavaborole should not be used if you are allergic to it or any of its ingredients. If you experience an allergic reaction, such as rash or swelling, stop using it and seek medical help. Always inform your doctor of any allergies or medical conditions before starting treatment.