Clobazam
.svg)
Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
Benzodiazepine
Controlled Drug Substance
YES
clobazam
Summary
Clobazam is used to treat seizures associated with epilepsy, which is a disorder where nerve cell activity in the brain is disturbed, causing seizures. It can also be used for anxiety disorders, which are conditions characterized by excessive worry or fear.
Clobazam works by enhancing the effects of GABA, which is a neurotransmitter that calms nerve activity in the brain. This helps reduce excessive nerve activity, leading to fewer seizures and a calming effect for anxiety.
Clobazam is usually taken orally, which means by mouth, once or twice daily. The starting dose for adults is typically 5 mg to 10 mg, with a maximum of 40 mg per day. Dosage may vary based on individual needs and doctor's recommendations.
Common side effects of Clobazam include drowsiness, which is feeling sleepy, dizziness, which is feeling lightheaded, and fatigue, which is feeling very tired. These effects are usually mild to moderate and affect more than 10% of users.
Clobazam can cause drowsiness, affecting your ability to drive. It may lead to dependence, which is a need to keep taking the drug. Avoid alcohol, which can increase side effects. Do not use if allergic to Clobazam or have severe liver disease, which is a serious liver condition.
Indications and Purpose
How does Clobazam work?
Clobazam works by enhancing the effects of a neurotransmitter called GABA, which is a chemical in the brain that helps calm nerve activity. Think of it like turning down the volume on a loud radio. By increasing GABA's calming effects, Clobazam reduces excessive nerve activity that can lead to seizures. This makes it effective for treating epilepsy and anxiety disorders. Clobazam helps stabilize brain activity, reducing the frequency and severity of seizures and providing a calming effect for anxiety.
Is Clobazam effective?
Clobazam is effective for treating seizures associated with epilepsy. It works by calming the brain and nerves, which helps reduce seizure frequency. Clinical studies support its effectiveness in managing seizures. Clobazam is often used as an add-on therapy with other anti-seizure medications. Its effectiveness may vary among individuals, so regular monitoring by your doctor is important. They will assess your response to the medication and make any necessary adjustments to your treatment plan to ensure optimal seizure control.
What is Clobazam?
Clobazam is a medication in the benzodiazepine class, which works by calming the brain and nerves. It's primarily used to treat seizures associated with epilepsy. Clobazam can also be used for anxiety disorders, providing a calming effect. It may be used alone or as an add-on therapy with other anti-seizure medications. Clobazam helps reduce the frequency and severity of seizures, improving the quality of life for individuals with epilepsy. Always follow your doctor's instructions when using Clobazam for any condition.
Directions for Use
For how long do I take Clobazam?
Clobazam is usually used for long-term treatment of conditions like epilepsy. The duration of use depends on your response to the medication and your doctor's recommendations. It's important to follow your doctor's instructions and not stop taking Clobazam without medical advice. Stopping suddenly can cause withdrawal symptoms or worsen your condition. Your doctor will guide you on how long to take Clobazam based on your individual health needs and treatment goals. Always consult your healthcare provider before making any changes to your medication.
How do I dispose of Clobazam?
To dispose of Clobazam, take it to a drug take-back program or collection site at a pharmacy or hospital. This ensures safe disposal without harming people or the environment. If a take-back program isn't available, you can throw Clobazam in the trash at home. First, remove it from its original container, mix it with something undesirable like used coffee grounds, seal the mixture in a plastic bag, and then throw it away. Always keep medications out of reach of children and pets.
How do I take Clobazam?
Take Clobazam as prescribed by your doctor. It's usually taken once or twice daily, with or without food. You can crush the tablet if needed. If you miss a dose, take it as soon as you remember, unless it's close to your next dose. In that case, skip the missed dose. Don't double up doses. Avoid alcohol while on Clobazam, as it can increase side effects. Always follow your doctor's specific instructions regarding food, beverages, and missed doses to ensure safe and effective use of Clobazam.
How long does it take for Clobazam to start working?
Clobazam starts working within 30 minutes to 2 hours after taking it. The full therapeutic effect may take several days to weeks, depending on the condition being treated. Factors like your metabolism, age, and overall health can affect how quickly Clobazam works. It's important to take Clobazam exactly as prescribed for the best results. If you have concerns about how long it takes to work, discuss them with your doctor. They can provide guidance based on your specific health situation.
How should I store Clobazam?
Store Clobazam at room temperature, away from moisture and light. Keep it in a tightly closed container to protect it from damage. Avoid storing it in humid places like bathrooms, as moisture can affect its effectiveness. If the packaging isn't child-resistant, transfer Clobazam to a container that children can't easily open. Always keep medications out of reach of children and pets. Regularly check the expiration date and properly dispose of any unused or expired Clobazam to ensure safety.
What is the usual dose of Clobazam?
The usual starting dose of Clobazam for adults is 5 mg to 10 mg once or twice daily. Your doctor may adjust the dose based on your response and needs. The maximum recommended dose is 40 mg per day. For children and the elderly, dose adjustments may be necessary, and they require careful monitoring. Always follow your doctor's specific dosing instructions for your health needs. Never adjust your dose without consulting your healthcare provider to ensure safe and effective use of Clobazam.
Warnings and Precautions
Can Clobazam be taken safely while breastfeeding?
Clobazam is not recommended while breastfeeding. It can pass into breast milk and may affect the nursing infant. The effects on milk supply are not well-studied. If you're taking Clobazam and wish to breastfeed, discuss this with your doctor. They can help determine the best course of action, possibly suggesting alternative medications that are safer for breastfeeding. Always consult your healthcare provider before making any decisions about medication use while breastfeeding to ensure the safety of your baby.
Can Clobazam be taken safely while pregnant?
Clobazam is not recommended during pregnancy unless absolutely necessary. Limited evidence is available on its safety during pregnancy. Animal studies suggest potential risks to the developing fetus. Uncontrolled seizures during pregnancy can harm both mother and baby. If you're pregnant or planning to become pregnant, talk to your doctor. They can help weigh the risks and benefits and create a treatment plan that ensures the safety of both you and your baby. Always follow your doctor's advice regarding medication use during pregnancy.
Can I take Clobazam with other prescription drugs?
Clobazam can interact with other medications, increasing the risk of side effects or reducing effectiveness. Major interactions include other central nervous system depressants, which can enhance drowsiness and dizziness. Moderate interactions include certain antidepressants and anticonvulsants, which may require dose adjustments. Always inform your doctor about all medications you are taking to manage these interactions safely. Your healthcare provider can help adjust your treatment plan to minimize risks and ensure the effectiveness of Clobazam.
Does Clobazam have adverse effects?
Adverse effects are unwanted reactions to a medication. Clobazam can cause drowsiness, dizziness, and fatigue, which are common adverse effects. These occur in more than 10% of users. Serious side effects include difficulty breathing or severe allergic reactions, which require immediate medical attention. If you experience any adverse effects, contact your doctor. They can help determine if Clobazam is the cause and adjust your treatment if necessary. Always report new or worsening symptoms to ensure your safety while taking Clobazam.
Does Clobazam have any safety warnings?
Yes, Clobazam has important safety warnings. It can cause drowsiness, which may impair your ability to drive or operate machinery. Clobazam may also increase the risk of dependence, especially with long-term use. Not adhering to these warnings can lead to accidents or addiction. Always follow your doctor's instructions and report any unusual symptoms. If you experience severe side effects like difficulty breathing or swelling, seek emergency medical help. Your doctor will provide guidance on how to use Clobazam safely.
Is Clobazam addictive?
Clobazam can be habit-forming, meaning it has the potential for addiction. This is because it affects brain chemistry, which can lead to physical or psychological dependence. Warning signs of dependence include cravings for the medication or taking more than prescribed. To prevent addiction, use Clobazam exactly as directed by your doctor. Avoid increasing the dose or frequency without medical advice. If you have concerns about dependence, discuss them with your healthcare provider. They can help manage your treatment safely.
Is Clobazam safe for the elderly?
Elderly individuals are more vulnerable to the side effects of Clobazam, such as drowsiness and dizziness, which can increase the risk of falls. Clobazam is generally safe for the elderly, but they may require lower doses and careful monitoring. The risk of cognitive impairment or confusion is also higher in older adults. Regular check-ups with a healthcare provider are important to ensure safe use. Always follow your doctor's advice and report any unusual symptoms while taking Clobazam.
Is it safe to drink alcohol while taking Clobazam?
It's best to avoid alcohol while taking Clobazam. Alcohol can increase the sedative effects of Clobazam, leading to increased drowsiness and dizziness. This combination can impair your ability to perform tasks that require alertness, like driving. Drinking alcohol with Clobazam may also increase the risk of side effects. If you choose to drink, do so in moderation and be aware of how your body reacts. Always talk to your doctor about alcohol use while taking Clobazam for personalized advice.
Is it safe to exercise while taking Clobazam?
You can exercise while taking Clobazam, but be cautious. Clobazam can cause drowsiness or dizziness, which might affect your balance and coordination during physical activity. Start with light exercises and gradually increase intensity as you see how your body responds. Stay hydrated and avoid strenuous activities if you feel dizzy or fatigued. If you experience any unusual symptoms during exercise, stop and rest. Always consult your doctor if you have concerns about exercising while taking Clobazam.
Is it safe to stop Clobazam?
It's not safe to stop Clobazam suddenly. Doing so can cause withdrawal symptoms like anxiety, tremors, or seizures. Clobazam is usually used for long-term treatment of conditions like epilepsy. If you need to stop taking it, your doctor will guide you on how to gradually reduce the dose to minimize withdrawal risks. Always consult your healthcare provider before making any changes to your medication regimen to ensure your safety and well-being.
What are the most common side effects of Clobazam?
Side effects are unwanted reactions to a medication. Common side effects of Clobazam include drowsiness, dizziness, and fatigue, affecting more than 10% of users. These side effects are usually mild to moderate. It's important to note that new symptoms may be coincidental and not related to Clobazam. If you experience side effects, talk to your doctor. They can help determine if Clobazam is the cause and suggest ways to manage the symptoms. Always consult your healthcare provider before stopping any medication.
Who should avoid taking Clobazam?
Clobazam should not be used if you have a known allergy to it or its ingredients. This is an absolute contraindication. Relative contraindications include severe liver disease, which may require caution and dose adjustments. Clobazam may also interact with other medications, increasing the risk of side effects. Always inform your doctor about your medical history and any other medications you are taking. They can help determine if Clobazam is safe for you and provide guidance on its use.
Forms / Brands
