Baclofen
Hiccup, Multiple Sclerosis ... show more
Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
NO
Pharmaceutical Class
Gamma-Aminobutyric Acid-ergic Agonist
Controlled Drug Substance
NO

Baclofen
Learn more about this medicine -
Click HereSummary
Baclofen is used to treat muscle spasms, stiffness, and pain caused by conditions like multiple sclerosis, spinal cord injuries, and other spinal cord diseases.
Baclofen works by lowering the activity in the spinal cord, which helps to reduce muscle stiffness and spasms. It is similar to a natural chemical in the brain called GABA, which helps to send messages that calm down the nerves and muscles.
Baclofen is typically taken orally. For adults, the usual daily dose is between 40-80 mg, divided into several doses throughout the day. The dosage is gradually increased to find the optimal dose. For children under 12 years, a doctor should be consulted for appropriate dosing.
Common side effects of Baclofen include feeling sleepy, dizziness, feeling weak, tiredness, confusion, headache, and trouble sleeping. Less common but serious side effects include seizures, heart problems, mood changes, hallucinations, and difficulty speaking.
Baclofen should not be used if you are allergic to it. It can cause drowsiness, so be careful when driving or operating machinery. Do not stop taking Baclofen abruptly as it can cause serious problems like hallucinations and seizures. It's also advisable to avoid alcohol while taking Baclofen.
Indications and Purpose
What is Baclofen used for?
Baclofen oral suspension is a medicine used to treat muscle stiffness and pain caused by multiple sclerosis, spinal cord injuries, and other spinal cord diseases. It works by relaxing the muscles and reducing pain. Baclofen oral suspension is taken by mouth.
How does Baclofen work?
Baclofen is a medicine that lowers the activity in the spinal cord, which helps to reduce muscle stiffness and spasms. It may also work in the brain to help with muscle control. Baclofen is similar to a natural chemical in the brain called GABA, which helps to send messages that calm down the nerves and muscles.
Is Baclofen effective?
Yes, Baclofen is effective for reducing muscle spasms, stiffness, and pain caused by conditions like multiple sclerosis or spinal cord injuries. It works by calming overactive nerve signals in the spinal cord. Its effectiveness varies by individual, and regular use as prescribed is key for optimal results. Always consult your doctor if symptoms persist or worsen.
How does one know if Baclofen is working?
You can tell Baclofen is working if you experience:
- Reduced muscle spasms, stiffness, or cramping.
- Improved ability to move or perform daily activities with less discomfort.
- Decreased pain associated with muscle tightness.
If symptoms persist or worsen, consult your doctor, as dosage adjustments may be needed.
Directions for Use
What is the usual dose of Baclofen?
For adults, the usual daily dose of Baclofen is typically between 40-80 mg, divided into several doses throughout the day. The dosage is gradually increased to find the optimal dose. For children under 12 years, safety and effectiveness have not been established, so a doctor should be consulted for appropriate dosing.
How do I take Baclofen?
Take Baclofen as prescribed by your doctor. Key instructions include:
- Dosage: Follow the exact dose and timing prescribed, usually starting low and gradually increasing.
- With or Without Food: It can be taken with food to reduce stomach upset.
- Avoid Alcohol: Combining Baclofen with alcohol can increase drowsiness and dizziness.
- Do Not Stop Abruptly: Taper off gradually under medical guidance to prevent withdrawal symptoms.
Always consult your doctor for specific instructions tailored to your condition.
For how long do I take Baclofen?
The duration of use can vary widely; some patients may take it for a few weeks, while others may require ongoing treatment for months or even years. Always consult with a healthcare provider for personalized guidance on the duration of treatment.
How long does it take for Baclofen to start working?
Baclofen typically starts working within 1 to 2 hours after taking an oral dose. For full benefits, especially with muscle spasms, it may take a few days to weeks of consistent use. Always follow your doctor’s instructions for proper dosing and adjustments.
How should I store Baclofen?
Store the medication at room temperature between 68°F to 77°F. It can be temporarily stored between 59°F and 86°F.
Warnings and Precautions
Who should avoid taking Baclofen?
Baclofen oral suspension should not be used if you are allergic to it. If you stop taking Baclofen oral suspension suddenly, it can cause serious problems like hallucinations, seizures, high fever, mental confusion, and muscle spasms. This can rarely lead to muscle breakdown, organ failure, and even death. So, it's important to gradually reduce your dose of Baclofen oral suspension when you stop taking it, unless your doctor tells you to stop suddenly. Baclofen oral suspension can also cause drowsiness, so be careful when driving or operating machinery.
Can I take Baclofen with other prescription drugs?
Baclofen oral solution is a type of medication that can cause drowsiness and sleepiness. These side effects may be worse if you take Baclofen with other medications or alcohol that also cause drowsiness, such as antidepressants, antihistamines, or sleeping pills. Combining Baclofen with these other substances can increase the risk of serious side effects, such as difficulty breathing, coma, or even death.
Can I take Baclofen with vitamins or supplements?
Yes, you can generally take Baclofen with vitamins or supplements, but some interactions should be considered:
- Magnesium or calcium supplements: May increase drowsiness when combined with Baclofen.
- Herbal supplements like valerian or kava: May enhance sedative effects, leading to excessive drowsiness.
Always consult your doctor or pharmacist to ensure there are no harmful interactions with your specific vitamins or supplements.
Can Baclofen be taken safely while pregnant?
Baclofen should be used during pregnancy only if clearly needed, as its safety is not fully established. It may be prescribed if the potential benefits outweigh the risks, but it’s essential to discuss with your doctor. Baclofen can cross the placenta, and its use requires close monitoring to minimize any potential effects on the baby.
Can Baclofen be taken safely while breastfeeding?
Baclofen, a medication, can pass into breast milk. We don't know how baclofen affects breast milk production or babies who breastfeed. When a mother stops taking baclofen or breastfeeding, babies may experience withdrawal symptoms. Breastfeeding offers benefits for both the mother and baby. Weigh these benefits against the mother's need for baclofen and any potential side effects on the baby. Generally, it's best for mothers to avoid breastfeeding while taking medication, as many medications can pass into breast milk.
Is Baclofen safe for the elderly?
Older adults need to start taking baclofen at a low dose and slowly increase it. This is because older people often have weaker livers, kidneys, or hearts, and may be taking other medicines. Starting low and going slow helps prevent problems.
Is it safe to exercise while taking Baclofen?
Baclofen can cause side effects like dizziness, weakness, and fatigue, which may limit the ability to exercise. If you experience these symptoms, it is advisable to avoid strenuous activities and consult your doctor for guidance on managing these side effects.
Is it safe to drink alcohol while taking Baclofen?
Drinking alcohol while taking Baclofen can increase the risk of side effects like drowsiness and sedation. Baclofen has central nervous system depressant effects, which can be enhanced by alcohol, leading to increased drowsiness and decreased alertness. It is advisable to avoid alcohol while taking Baclofen.