Amlodipine
Hypertension, Variant Angina Pectoris ... show more
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
YES
Known Teratogen
NO
Pharmaceutical Class
Calcium Channel Blocker and Dihydropyridine Calcium Channel Blocker
Controlled Drug Substance
NO
Amlodipine
Learn more about this medicine -
Click HereSummary
Amlodipine is primarily used to treat high blood pressure, also known as hypertension, and to prevent chest pain or angina. It may also be prescribed for other heart-related conditions.
Amlodipine is a type of medicine known as a calcium channel blocker. It works by relaxing the blood vessels, making it easier for the heart to pump blood. This helps lower blood pressure and reduce chest pain.
The recommended starting dose for adults is 5 mg once daily, with a maximum of 10 mg daily. Elderly patients or those with liver problems may start with a lower dose of 2.5 mg once daily. For children aged 6 to 17 years, the effective dose is 2.5-5 mg once daily.
Common side effects may include headache, dizziness, and swelling in the ankles. Other side effects can include drowsiness, stomach upset, and mood changes.
People with severe low blood pressure, certain heart conditions like severe aortic stenosis, or those with a history of allergic reactions to Amlodipine should avoid it. It's also important to avoid grapefruit juice while taking amlodipine, as it can affect how the medication works.
Indications and Purpose
What is Amlodipine used for?
Amlodipine is used to treat high blood pressure and angina. It helps relax blood vessels, allowing blood to flow more easily, which lowers blood pressure and reduces chest pain. It can be used alone or with other treatments like diet and exercise.
How does Amlodipine work?
Amlodipine works by relaxing the blood vessels, similar to how a garden hose widens to allow more water to flow through. This relaxation helps lower blood pressure and reduces the workload on the heart, easing symptoms like chest pain.
Is Amlodipine effective?
Amlodipine is primarily used to treat high blood pressure and angina. It works by relaxing blood vessels, allowing blood to flow more easily. Clinical trials have shown that Amlodipine effectively lowers blood pressure and reduces the frequency of angina attacks.
How does one know if Amlodipine is working?
Amlodipine is used to treat high blood pressure and angina. You can tell it's working if your blood pressure readings improve or if you experience fewer angina attacks. Regular monitoring by your healthcare provider will help assess its effectiveness.
Directions for Use
What is the usual dose of Amlodipine?
The usual starting dose of Amlodipine for adults is 5 mg once daily. Depending on the individual's response, the dose may be adjusted by a healthcare provider, with a maximum recommended dose of 10 mg per day. For elderly patients or those with liver impairment, a lower starting dose may be considered. Always follow your healthcare provider's instructions for dosing.
How do I take Amlodipine?
Take Amlodipine once daily, with or without food. There are no specific dietary restrictions, but it's important to follow your healthcare provider's instructions regarding timing and frequency.
For how long do I take Amlodipine?
Amlodipine is typically used for long-term management of chronic conditions like hypertension. The duration of use depends on the individual's condition and response to treatment. It's important to follow your healthcare provider's instructions regarding the duration of use.
How long does it take for Amlodipine to start working?
Amlodipine starts working within a few hours, but it may take several weeks to achieve its full effect. Individual factors like age, weight, and overall health can affect how quickly it works. Always follow your healthcare provider's instructions.
How should I store Amlodipine?
Store Amlodipine at room temperature, away from moisture and light. Keep it out of reach of children. Avoid storing it in the bathroom or near a sink to prevent exposure to moisture.
Warnings and Precautions
Who should avoid taking Amlodipine?
Amlodipine should not be used in individuals with known allergies to it. Caution is advised in patients with severe low blood pressure, heart failure, or liver impairment. Always inform your healthcare provider about your medical history before starting Amlodipine.
Can I take Amlodipine with other prescription drugs?
Amlodipine can interact with other blood pressure medications, increasing the risk of low blood pressure. It may also interact with certain heart medications, requiring dose adjustments. Always inform your healthcare provider about all medications you are taking.
Can I take Amlodipine with vitamins or supplements?
There are no confirmed interactions between Amlodipine and specific vitamins or supplements. However, it's important to inform your healthcare provider about all medications and supplements you are taking. This ensures safe and effective use of Amlodipine and helps monitor any potential nutrient depletions or adverse effects.
Can Amlodipine be taken safely while pregnant?
From all available and reliable information, there is no confirmed data on this. Please consult a doctor for personalized advice.
Can Amlodipine be taken safely while breastfeeding?
From all available and reliable information, there is no confirmed data on this. Please consult a doctor for personalized advice.
Is Amlodipine safe for the elderly?
Elderly patients may be more sensitive to the effects of Amlodipine, particularly the risk of low blood pressure. It's important to start with a lower dose and monitor for symptoms like dizziness or fainting. Always follow your healthcare provider's instructions.
Is it safe to exercise while taking Amlodipine?
Most people tolerate Amlodipine well, and it should not limit your ability to exercise. However, if you experience dizziness or fatigue during physical activity, take precautions and consult your healthcare provider for personalized advice.
Is it safe to drink alcohol while taking Amlodipine?
Occasional or moderate alcohol consumption is generally not advisable while taking Amlodipine. Alcohol can enhance the blood pressure-lowering effects of Amlodipine, leading to dizziness or fainting. It is recommended to limit alcohol intake to avoid these potential side effects. If you choose to drink, do so in moderation and be aware of how your body reacts. Always consult your healthcare provider for personalized advice.
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