Amlodipine
Hypertension, Variant Angina Pectoris ... show more
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
YES
Known Teratogen
NO
Pharmaceutical Class
Calcium Channel Blocker and Dihydropyridine Calcium Channel Blocker
Controlled Drug Substance
NO
Amlodipine
Summary
Amlodipine is primarily used to treat high blood pressure, also known as hypertension, and to prevent chest pain or angina. It may also be prescribed for other heart-related conditions.
Amlodipine is a type of medicine known as a calcium channel blocker. It works by relaxing the blood vessels, making it easier for the heart to pump blood. This helps lower blood pressure and reduce chest pain.
The recommended starting dose for adults is 5 mg once daily, with a maximum of 10 mg daily. Elderly patients or those with liver problems may start with a lower dose of 2.5 mg once daily. For children aged 6 to 17 years, the effective dose is 2.5-5 mg once daily.
Common side effects may include headache, dizziness, and swelling in the ankles. Other side effects can include drowsiness, stomach upset, and mood changes.
People with severe low blood pressure, certain heart conditions like severe aortic stenosis, or those with a history of allergic reactions to Amlodipine should avoid it. It's also important to avoid grapefruit juice while taking amlodipine, as it can affect how the medication works.
Indications and Purpose
How does Amlodipine work?
Amlodipine works by relaxing the blood vessels, similar to how a garden hose widens to allow more water to flow through. This relaxation helps lower blood pressure and reduces the workload on the heart, easing symptoms like chest pain.
Is Amlodipine effective?
Amlodipine is primarily used to treat high blood pressure and angina. It works by relaxing blood vessels, allowing blood to flow more easily. Clinical trials have shown that Amlodipine effectively lowers blood pressure and reduces the frequency of angina attacks.
What is Amlodipine?
Amlodipine is a medication used primarily to treat high blood pressure and angina. It works by relaxing blood vessels, allowing blood to flow more easily. This helps lower blood pressure and reduce chest pain.
Directions for Use
For how long do I take Amlodipine?
Amlodipine is typically used for long-term management of chronic conditions like hypertension. The duration of use depends on the individual's condition and response to treatment. It's important to follow your healthcare provider's instructions regarding the duration of use.
How do I dispose of Amlodipine?
If you can, bring unused medicines to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of this medicine properly so they don't harm people or the environment. If you can't find a take-back program, you can throw most medicines in the trash at home. But first, take them out of their original containers, mix them with something undesirable like used coffee grounds, seal the mixture in a plastic bag and throw it away.
How do I take Amlodipine?
Take Amlodipine once daily, with or without food. There are no specific dietary restrictions, but it's important to follow your healthcare provider's instructions regarding timing and frequency.
How long does it take for Amlodipine to start working?
Amlodipine starts working within a few hours, but it may take several weeks to achieve its full effect. Individual factors like age, weight, and overall health can affect how quickly it works. Always follow your healthcare provider's instructions.
How should I store Amlodipine?
Store Amlodipine at room temperature, away from moisture and light. Keep it out of reach of children. Avoid storing it in the bathroom or near a sink to prevent exposure to moisture.
What is the usual dose of Amlodipine?
The usual starting dose of Amlodipine for adults is 5 mg once daily. Depending on the individual's response, the dose may be adjusted by a healthcare provider, with a maximum recommended dose of 10 mg per day. For elderly patients or those with liver impairment, a lower starting dose may be considered. Always follow your healthcare provider's instructions for dosing.
Warnings and Precautions
Can Amlodipine be taken safely while breastfeeding?
Amlodipine is excreted into breast milk, but the amount is generally low. There is limited information on adverse effects on breastfed infants, and no significant effects on milk supply have been reported. Due to the lack of comprehensive data, it's important to consult your healthcare provider before using Amlodipine while breastfeeding to weigh the benefits and risks.
Can Amlodipine be taken safely while pregnant?
The safety of Amlodipine during pregnancy is not well established, and it is generally not recommended unless absolutely necessary. There is limited data on its effects on pregnant women, and potential risks to the fetus are not fully understood. If you are pregnant or planning to become pregnant, consult your healthcare provider to discuss the risks and benefits before using Amlodipine.
Can I take Amlodipine with other prescription drugs?
Amlodipine can interact with other blood pressure medications, increasing the risk of low blood pressure. It may also interact with certain heart medications, requiring dose adjustments. Always inform your healthcare provider about all medications you are taking.
Does Amlodipine have adverse effects?
Adverse effects are harmful or unintended reactions to a medication. Amlodipine can cause adverse effects such as severe dizziness, fainting, or an irregular heartbeat. These are rare but require immediate medical attention. It's crucial to report any new symptoms to a healthcare provider and consult them before stopping the medication.
Does Amlodipine have any safety warnings?
Amlodipine may cause low blood pressure, especially when starting the medication or increasing the dose. Symptoms to watch for include dizziness, lightheadedness, or fainting. It's important to monitor these symptoms and consult your healthcare provider if they occur.
Is Amlodipine addictive?
Amlodipine has no known potential for dependence or addiction. It is not habit-forming, and there are no behaviors or warning signs associated with addiction to this medication.
Is Amlodipine safe for the elderly?
Elderly patients may be more sensitive to the effects of Amlodipine, particularly the risk of low blood pressure. It's important to start with a lower dose and monitor for symptoms like dizziness or fainting. Always follow your healthcare provider's instructions.
Is it safe to drink alcohol while taking Amlodipine?
Occasional or moderate alcohol consumption is generally not advisable while taking Amlodipine. Alcohol can enhance the blood pressure-lowering effects of Amlodipine, leading to dizziness or fainting. It is recommended to limit alcohol intake to avoid these potential side effects. If you choose to drink, do so in moderation and be aware of how your body reacts. Always consult your healthcare provider for personalized advice.
Is it safe to exercise while taking Amlodipine?
Most people tolerate Amlodipine well, and it should not limit your ability to exercise. However, if you experience dizziness or fatigue during physical activity, take precautions and consult your healthcare provider for personalized advice.
Is it safe to stop Amlodipine?
Amlodipine is used for managing chronic conditions like hypertension. Stopping it abruptly can lead to a rebound increase in blood pressure, which may be dangerous. Always consult your doctor before stopping Amlodipine to avoid potential complications.
What are the most common side effects of Amlodipine?
A side effect is an unwanted symptom caused by medical treatment. Common side effects of Amlodipine include swelling of the ankles or feet, dizziness, flushing, headache, and fatigue. These side effects are generally mild and may occur in more than 1 in 10 people. It's important to note that new symptoms can appear when starting any new medication, and they may not be related to the medicine itself. Always consult a healthcare provider before stopping any medication.
Who should avoid taking Amlodipine?
Amlodipine should not be used in individuals with known allergies to it. Caution is advised in patients with severe low blood pressure, heart failure, or liver impairment. Always inform your healthcare provider about your medical history before starting Amlodipine.
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