velaf (VENLAFAXINE)

What is Velaf?

Velaf is commonly used to treat depression, anxiety disorders, and panic disorders. It works by increasing the levels of serotonin and norepinephrine, two neurotransmitters in the brain, which help regulate mood, anxiety, and stress responses. By balancing these chemicals, Velaf can improve mood and reduce symptoms of anxiety and depression. It is typically prescribed as an extended-release tablet taken once daily.

What is the usual dose of Velaf?

The medicine starts at a low dose of 75 mg once a day with food. The doctor might increase the dose slowly, by no more than 75 mg every four days, to a maximum of 225 mg daily. Some people might begin with a smaller dose of 37.5 mg for a few days before going up to 75 mg. This information is only for adults.

How do I take Velaf?

Velaf should be taken with food to reduce the risk of stomach upset. It is important to swallow the extended-release capsule whole without crushing or chewing. There are no specific food restrictions, but avoiding alcohol is recommended, as it may increase the risk of side effects. Always follow the doctor’s instructions for dosage and usage.

For how long do I take Velaf?

Velaf is typically used for 6-12 months for most conditions, with longer use for recurrent or chronic cases. Duration depends on the individual’s needs, and tapering off should always be done under medical guidance.

What is Velaf used for?

Velaf is primarily indicated for the treatment of:

1. Major depressive disorder (MDD) – to alleviate symptoms of depression.
2. Generalized anxiety disorder (GAD) – to reduce anxiety and related symptoms.
3. Social anxiety disorder (SAD) – to help with social phobia and anxiety in social settings.
4. Panic disorder – to reduce the frequency and intensity of panic attacks.
5. Post-traumatic stress disorder (PTSD) (off-label) – to manage symptoms related to trauma and stress.

How long does it take for Velaf to start working?

Velaf typically starts showing effects after 1 to 2 weeks of use, but it may take 4 to 6 weeks to experience the full therapeutic benefits, especially for conditions like depression or anxiety. Individual responses can vary, so it's important to follow the prescribed treatment plan and consult a doctor if there's no improvement.

Is Velaf effective?

Velaf is proven effective in treating depression, anxiety, and panic disorders by increasing serotonin and norepinephrine levels. Clinical studies show it improves symptoms, especially in severe cases, and is more effective than some other antidepressants.

How does one know if Velaf is working?

The benefit of Velaf is evaluated by monitoring the improvement in symptoms of depression, anxiety, and panic disorders through regular assessments. This includes observing changes in mood, behavior, and overall functioning, often using rating scales like the Hamilton Depression Rating Scale (HDRS). Blood tests may also be conducted to check for appropriate drug levels and side effects.

How does Velaf work?

Velaf works by increasing the levels of two neurotransmitters in the brain: serotonin and norepinephrine. It is classified as a serotonin-norepinephrine reuptake inhibitor (SNRI). By blocking the reuptake of these neurotransmitters, Velaf helps improve mood, reduce anxiety, and alleviate depressive symptoms. In higher doses, it also inhibits the reuptake of dopamine. This mechanism of action helps regulate mood, anxiety, and stress responses.

Who should avoid taking Velaf?

Velaf should be used with caution in individuals with a history of high blood pressure, as it can increase blood pressure. It is contraindicated in people with hypersensitivity to the drug or monoamine oxidase inhibitors (MAOIs). Caution is also needed for those with a history of seizures, heart disease, or suicidal thoughts. Abrupt discontinuation can cause withdrawal symptoms.

Can I take Velaf with vitamins or supplements?

Velaf may interact with certain vitamins and supplements. For example, taking it with St. John's Wort can increase the risk of serotonin syndrome, a potentially life-threatening condition. High doses of Vitamin C or other acidic supplements may also alter Velaf absorption. Always consult with a healthcare provider before combining Velaf with supplements.

Can I take Velaf with other prescription drugs?

Velaf can interact with several prescription medications, including:

1. Monoamine oxidase inhibitors (MAOIs): Combining Velaf with MAOIs can cause a dangerous condition called serotonin syndrome.
2. Other antidepressants (SSRIs, SNRIs, tricyclics): Increased risk of serotonin syndrome and enhanced side effects.
3. Antiplatelet drugs/NSAIDs: May increase the risk of bleeding.
4. Cimetidine: Can raise Velaf levels, increasing the risk of side effects.
5. Antihypertensive medications: Velaf may reduce the effectiveness of blood pressure medications.

Can Velaf be taken safely while pregnant?

Velaf is classified as a Category C medication during pregnancy, meaning risk to the fetus cannot be ruled out. Studies in animals have shown adverse effects, but there are no well-controlled studies in humans. It should only be used during pregnancy if the potential benefits outweigh the risks. Velaf use during pregnancy, especially in the third trimester, may increase the risk of complications such as preterm birth, low birth weight, and withdrawal symptoms in newborns. Always consult a doctor before using it during pregnancy.

Can Velaf be taken safely while breastfeeding?

Velaf is excreted in breast milk, but the effects on a nursing infant are not fully known. Studies suggest that the medication may pose a risk of side effects in the infant, such as drowsiness, poor feeding, and irritability. Due to potential risks, breastfeeding mothers should discuss the use of Velaf with their healthcare provider to weigh the benefits and risks.

Is Velaf safe for the elderly?

Older people don't usually need a lower dose of Velaf just because of their age. However, if they have high blood pressure or liver problems, and they're also taking cimetidine, doctors need to be extra careful because the combination might cause more side effects. Older people also have a slightly higher chance of developing low sodium levels in their blood while taking this medicine. Otherwise, Velaf seems to work and be safe similarly in older and younger people.

How should I store Velaf?

Keep the medicine in its original container at room temperature between 59°F and 86°F (15°C and 30°C). Make sure the container is tightly closed to prevent moisture or air from getting inside.

Does Velaf make people tired or drowsy?

Yes, somnolence (sleepiness) was reported in 17% of patients in major depressive disorder trials and 16% of patients in social anxiety disorder trials. Fatigue was reported in 8% of patients with major depressive disorder and 17% of patients with social anxiety disorder. If you experience these symptoms, consult your doctor.

Does Velaf cause stomach upset?

Yes, this medicine can cause stomach upset. Nausea was reported in 31% of patients with major depressive disorder and 29% of patients with social anxiety disorder. Other gastrointestinal complaints include dry mouth (12% MDD, 17% SAD), anorexia (8% MDD, 20% SAD), constipation (8% MDD, 8% SAD), vomiting (4% MDD, 3% SAD) and flatulence (4% MDD). If you experience gastrointestinal side effects, contact your healthcare provider.

Does Velaf affect sleep?

Yes, insomnia was reported in 17% of patients with major depressive disorder and 23% of patients with social anxiety disorder. If you experience a change in sleep, consult your doctor.

Does Velaf make it hard to think or concentrate?

Dizziness was reported in 20% of patients with major depressive disorder and 16% of patients with social anxiety disorder. Nervousness was reported in 10% of patients with major depressive disorder and 11% of patients with social anxiety disorder. If you experience cognitive side effects, talk to your doctor.

Does Velaf affect mood?

Depression and agitation were reported in 3% of patients with major depressive disorder. Anxiety was reported in 5% of patients with social anxiety disorder. If you experience a mental health side effect, contact your healthcare provider immediately.

Does Velaf interfere with sexual function?

Abnormal ejaculation was reported in 16% of male patients with major depressive disorder and impotence in 4%. Libido decreased was reported in 3% of patients with major depressive disorder and 9% of patients with social anxiety disorder. In females with social anxiety disorder, orgasmic dysfunction was reported at 8%. If you experience sexual side effects, talk to your doctor.

Does Velaf affect appetite?

Anorexia (loss of appetite) was reported in 8% of patients with major depressive disorder and 20% of patients with social anxiety disorder. If you experience changes in appetite, consult your doctor.

Does Velaf cause weight gain?

Weight loss was reported in 3% of patients with major depressive disorder and 4% of patients with social anxiety disorder. If you experience weight changes, consult your doctor.

Does Velaf cause headaches?

Headache was reported in 34% of patients in social anxiety disorder. If you experience headaches while taking this medication, talk to your doctor.

Does Velaf limit driving?

This medicine can make you sleepy. Don't drive or use heavy machinery until you know how it affects you. If you have trouble driving, stop right away.

Is it safe to drink alcohol while taking Velaf?

Velaf is a medicine. Mixing it with alcohol can make serious side effects more likely. It's best to avoid alcohol completely while you're taking this medication.

Is it safe to drink coffee or tea while taking Velaf?

The information regarding any specific interactions between caffeinated beverages like coffee or tea and Velaf ia not found.

Is it safe to exercise while taking Velaf?

The information regarding any specific interactions between exercise and Velaf is not found.

What are Velaf possible harms and risks?

Common side effects of Velaf include nausea, dry mouth, dizziness, insomnia, and sweating. Significant adverse effects may include increased blood pressure, sexual dysfunction, weight changes, and serotonin syndrome. Rare but serious effects include suicidal thoughts, particularly in young adults, and an increased risk of bleeding. Monitoring blood pressure and mental health is important during treatment.