bispec (SOLIFENACIN)
Introduction to bispec
Bispec is a medication primarily used to manage symptoms of an overactive bladder. It helps individuals who experience frequent urination, urgency, and incontinence by improving... See More

What is Bispec?
Bispec is used primarily to treat overactive bladder symptoms, such as frequent urination, urgency, and incontinence. It works by blocking muscarinic receptors in the bladder, reducing involuntary bladder contractions and increasing the bladder's capacity to hold urine. This helps improve bladder control and reduce urgency or leakage.

What is the usual dose of Bispec?
Bispec succinate is a medicine. For adults, the usual starting dose is 5 milligrams once a day. A doctor might increase this to 10 milligrams if the first dose works well and doesn't cause problems. This medicine is not for children.

How do I take Bispec?
- Dosage: Typically 5 mg once daily, may increase to 10 mg based on response.
- With or Without Food: Can be taken with or without food.
- Food Restrictions: No specific food restrictions are required, but avoid excessive fluid intake before bed to reduce nighttime urination.
- Other Tips: Swallow the tablet whole; do not chew or crush. Always follow the dosage instructions provided by your doctor.

For how long do I take Bispec?
A medicine called Bispec succinate was tested. Most people who took it for 12 weeks continued for a much longer time (40 weeks). Side effects stayed about the same whether people took the medicine for 3 months or a full year.

What disease or symptom is Bispec used for?
Bispec is used to treat overactive bladder (OAB), helping manage symptoms like urinary urgency, frequency, and incontinence. It works by reducing involuntary bladder contractions.

How long does it take for Bispec to start working?
Bispec may start showing effects within 1 to 2 weeks of use, though it can take up to 4 to 6 weeks for the full benefits to be noticed in managing overactive bladder symptoms like urgency and frequency. It’s important to follow your doctor's recommendations and give the medicine time to work.

Is Bispec effective?
Clinical studies have shown that Bispec effectively reduces symptoms of overactive bladder (OAB), including urgency, frequency, and incontinence. In trials, patients experienced significant improvement in bladder control, with many reporting fewer episodes of leakage and urgency. It has been proven to be effective in both short-term and long-term use, with a well-established safety profile. These findings are supported by medical guidelines and real-world data.

How do I know if Bispec is working?
- Frequency of urination: Reduction in the number of times a person needs to urinate.
- Urgency: Decreased feelings of urgency or the sudden need to urinate.
- Incontinence episodes: Fewer episodes of urine leakage.
- Quality of life: Improvement in daily activities and comfort.

How does Bispec work?
Bispec works by blocking muscarinic receptors in the bladder, specifically the M3 receptors, which are responsible for bladder muscle contractions. By inhibiting these receptors, it reduces involuntary contractions, increases bladder capacity, and helps improve bladder control, reducing symptoms like urgency, frequency, and incontinence in overactive bladder.

Who should avoid taking Bispec?
Bispec should be used with caution in elderly patients, those with urinary retention, and people in hot environments due to heatstroke risk. It is contraindicated in individuals with severe liver or kidney impairment, urinary retention, or gastric retention. Avoid use if allergic to the medication. Always consult a doctor before using, especially if you have any of these conditions.

Can I take Bispec with other prescription drugs?
- Anticholinergics (e.g., atropine, antihistamines): May increase the risk of dry mouth, blurred vision, and urinary retention.
- CYP3A4 Inhibitors (e.g., ketoconazole, clarithromycin): Can increase Bispec levels, raising the risk of side effects.
- Diuretics: May enhance the risk of urinary retention or constipation.

Can Bispec be taken safely while pregnant?
Bispec is classified as pregnancy category C, meaning that its safety during pregnancy has not been well established. Animal studies have shown some risks, but there are no sufficient human studies. It should only be used during pregnancy if the benefit outweighs the risk. Always consult a healthcare provider before using Bispec during pregnancy.

Can Bispec be taken safely while breastfeeding?
Bispec is excreted in breast milk in small amounts, but the effects on a nursing infant are not well studied. Due to potential risks like dry mouth or urinary retention, it is advised to use caution during breastfeeding. If necessary, a doctor may recommend alternative treatments or advise temporarily discontinuing breastfeeding while using the medication. Always consult a healthcare provider.

Is Bispec safe for the elderly?
Bispec works similarly well and is equally safe for older and younger adults. However, people with kidney or liver problems might need a lower dose. If their kidneys aren't working well, the highest dose should be 5mg once a day. The same 5mg once daily limit applies to people with moderately damaged livers. It's not recommended at all for those with severely damaged livers.

How should I store Bispec?
Store Bispec at room temperature (68°F to 77°F or 20°C to 25°C), away from heat, moisture, and direct light. Do not freeze. Keep the medication in a cool, dry place and ensure the bottle is tightly closed. Store out of reach of children, and follow the storage instructions provided on the label for optimal effectiveness.

Does Bispec make people tired or drowsy?
Bispec may cause drowsiness or dizziness in some people, but it is not a common side effect. If you experience significant tiredness, you should avoid activities that require full alertness, such as driving.

Does Bispec cause stomach upset?
Yes, some individuals may experience mild stomach upset, including nausea or dry mouth, as side effects of Bispec.

Does Bispec affect sleep?
The medicine might make you sleepy. It's also been linked to confusion and seeing or hearing things that aren't there. If you have trouble sleeping because of this medicine, talk to your doctor. They might lower your dose or have you stop taking it.

Does Bispec make it hard to think or concentrate?
Bispec can cause cognitive side effects like dizziness or difficulty concentrating in some individuals, particularly when starting the medication or when combined with other sedating drugs.

Does Bispec affect mood?
Bispec does not typically affect mood. However, some people may experience irritability or other mood changes due to the discomfort caused by side effects like dry mouth or urinary retention.

Does Bispec interfere with sexual function?
Bispec may cause sexual side effects such as difficulty achieving an erection or dryness, though these are not very common.

Does Bispec affect appetite?
Bispec generally does not affect appetite. However, its side effects, like dry mouth or discomfort, may indirectly impact eating habits.

Does Bispec cause weight gain?
Bispec is not associated with weight gain, though any changes in appetite or fluid retention due to side effects might lead to temporary changes.

Does Bispec cause headaches?
Bispec can cause headaches. This is because it affects the brain. If you get a headache while taking it, watch for other symptoms like dizziness or confusion. If the headache gets worse or you're worried, talk to your doctor. They might lower your dose or have you stop taking the medicine.

Does Bispec limit driving?
Bispec succinate can make you blurry-eyed or sleepy. This means you might not be able to drive safely. If you have trouble driving while on this medicine, stop driving and call your doctor.

Is it safe to drink alcohol while taking Bispec?
Alcohol may increase the risk of certain side effects like dizziness or drowsiness when taking Bispec. It’s best to limit alcohol intake or avoid it if possible.

Is it safe to drink coffee or tea while taking Bispec?
Yes, it is generally safe to drink coffee or tea while taking Bispec. However, caffeine can be a mild irritant to the bladder in some people, so monitor for any increased urinary urgency.

Is it safe to exercise while taking Bispec?
Yes, it is safe to exercise while taking Bispec. Just be mindful of side effects like dizziness or dry mouth, which could make physical activity more uncomfortable.

What are the most common side effects of Bispec?
A side effect is an unwanted or unexpected symptom caused by a medicine. For this medicine, common side effects may include nausea, which is feeling sick to your stomach, dizziness, which is feeling lightheaded or unsteady, headache, which is pain in the head, fatigue, which is feeling very tired, and dry mouth, which is a lack of saliva. The frequency of these side effects can vary, but they are generally considered common. It's important to note that when starting a new medicine, people might experience new symptoms that could be coincidental, unrelated, or temporary. These symptoms might also be due to another health issue. Always talk to a healthcare provider before stopping any medicine, as they can provide guidance on managing side effects and ensure your treatment is safe and effective.

Does Bispec have adverse effects?
Adverse effects, which are unwanted or harmful reactions to a medicine, can occur with any medication. For this medicine, common adverse effects might include nausea, headache, dizziness, fatigue, and dry mouth. These effects can vary in how often they occur, but they are generally not severe. However, there are serious adverse effects that, although rare, need immediate medical attention. These might include severe allergic reactions, which can cause difficulty breathing or swelling, or signs of liver damage, such as yellowing of the skin or eyes. It's crucial to report any new or worsening symptoms to a healthcare provider. Never stop taking a medicine without first consulting a healthcare professional, as they can provide guidance on how to manage side effects safely.

Is Bispec addictive?
To determine if a medicine is addictive, we first need to know its name. If the medicine is known to be habit-forming, it means it can cause dependence, which is when the body or mind feels a need for the drug. This can happen because the medicine changes how the brain works, making it hard to stop using it. Warning signs of addiction include needing more of the medicine to feel the same effects, using it even when it causes problems, or feeling bad when not using it. To avoid addiction, follow the doctor's instructions, don't take more than prescribed, and talk to a healthcare provider if you have concerns. If the medicine has no known potential for addiction, it's safe to say it doesn't cause dependence.

Does Bispec have any safety warnings?
This medicine does have safety warnings. One key warning is the risk of allergic reactions, which occur when the body's immune system overreacts to the medicine. This can lead to symptoms like rash, itching, swelling, or difficulty breathing. If you notice these symptoms, seek medical help immediately. Another warning is the potential for liver damage, which can happen if the medicine is processed by the liver and causes harm. Signs to watch for include yellowing of the skin or eyes, dark urine, or severe fatigue. If these occur, contact a healthcare provider. Lastly, there is a warning about interactions with other medications, which can alter the effectiveness or increase side effects. Symptoms to monitor include unusual tiredness, dizziness, or changes in heart rate. Always inform your doctor about any other medicines you are taking.

Is it safe to stop Bispec?
To determine if it's safe to stop a medicine, first identify its purpose. If it's for managing a chronic condition like hypertension or diabetes, stopping it suddenly can lead to serious health risks, such as uncontrolled blood pressure or blood sugar levels. If the medicine is for symptomatic relief or treating an acute condition, like an infection, stopping it prematurely might result in the return of symptoms or incomplete treatment. Some medicines can cause withdrawal or rebound symptoms if stopped abruptly, which can be uncomfortable or even dangerous. For example, stopping certain antidepressants suddenly can lead to withdrawal symptoms. It's crucial to consult with a doctor before stopping any medicine to ensure it's done safely and appropriately. They can provide guidance on how to taper off the medicine if necessary, minimizing any potential risks.

How do I dispose of Bispec?
If you can, bring unused medicines to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of this medicine properly so they don't harm people or the environment. If you can't find a take-back program, you can throw most medicines in the trash at home. But first, take them out of their original containers, mix them with something undesirable like used coffee grounds, seal the mixture in a plastic bag and throw it away.

What are Bispec possible harms and risks?
Common Side Effects: Dry mouth, constipation, blurred vision, headache, dizziness.
Significant Adverse Effects: Severe allergic reactions, difficulty urinating, confusion (especially in older adults), heatstroke risk.
Contact a healthcare provider if severe effects occur.
Available in 2 variations

Bispec 5mg Tablet
Solifenacin (5mg)
strip of 15 tablets

Bispec 10MG Tablet
Solifenacin (10mg)
strip of 15 tablets